Supplements for Fatigue

Natural formula supplements for tiredness

For a complete approach, we’re introducing not one, not two, but three supplements with natural formulas to take together for energy and vitality!

The Energy Plus Programme is the result of combining Energea+ New Formula, Glutatione Forte and Goji Juice, which, thanks to their specific active ingredients, allow you to:

• counteract accumulated stress and tiredness,
• promote the production of new energy,
• support your body in a 100% natural way.

Energea+ New Formula

With a formulation containing the active ingredients of Spirulina1, Ashwagandha2, Royal Jelly3, Ginseng4, Grape Seed5 and Manganese6, it is the natural energy supplement par excellence.

The ingredients of Energea+ New Formula contribute to your physical and mental wellbeing because they don’t work by stimulating your nervous system (its formulation contains no caffeine); instead, they promote the production of new energy in a 100% natural way, thanks to the action of amino acids, antioxidants and trace elements.

In particular, they support the functions of the parts of the cell responsible for producing energy (the mitochondria!)2.

The result: you’ll have strength and energy to spare!

Glutatione Forte

Your body will thank you: with the Glutatione Forte formula you take in Reduced Glutathione7 and Quercetin8 at the maximum permitted levels, and both at the same time!

In true Salugea style, these active ingredients are 100% natural!

The reduced Glutathione in Glutatione Forte is obtained through biofermentation and, within the formulation as a whole, is “protected” by the presence of phytocomplexes, so that your body can absorb it optimally9, also thanks to the acid-resistant capsule that encloses the formulation.

What’s more, thanks to the presence of Naringenin10, Selenium11 and the patented ingredient OxiP®12-13-14-15:

• you feel more energetic,
• you help your body eliminate toxins,
• you support your immune system.

Goji Juice

It is one of our liquid supplements and is obtained by pressing organic Goji berries.

Goji berries have become part of our diet precisely because of their undisputed antioxidant and tonic properties16.

Goji juice is a natural energiser17 that can stimulate your body’s vitality and stamina, without the need to resort to stimulants.

It also provides valuable support for the immune defences18, which are put to an even tougher test in situations of stress and tiredness.

Supplements for physical and mental tiredness

When you’re tired, both your body and your mind suffer, and it’s important to support them both.

To support your mind, you can rely on Memosan, a natural supplement whose formula supports memory and concentration when you feel exhausted.

Thanks to Bacopa19, Schisandra20, Reishi21, Rhodiola22 and Centella23, Memosan’s winning synergy nourishes the brain, promoting the oxygenation of the tissues involved.

With these ingredients, your mind will be clear and fresh, you won’t feel overwhelmed by your daily commitments and you’ll get through your days with efficiency and vitality.

In particular, thanks to specific compounds called lignans20, Schisandra boasts adaptogenic properties, i.e. properties that help the body adapt to the most difficult situations, such as a period of intense stress.

You can finally blow a raspberry at chronic tiredness and get through your days at your best.

To support your mind and sustain it through moments of pessimism, tiredness and tension, we have formulated Rilassa Mente, with Griffonia24, Jujube25, Lemon Balm26 and Hawthorn27.

Thanks to its natural active ingredients, you support mental clarity and live life with optimism!

Specifically, Jujube supports the body in coping with external stimuli, which are constant and ever-changing throughout your day.

For even greater support that also looks after your body, we suggest Omega 3 Krill Oil.

Omega 3s, EPA and DHA, are nutrients described as “essential” because you need to obtain them through your diet in order to benefit from them.

Omega 3 Krill Oil is made with Omega 3s obtained from the oil of Krill, a small Antarctic crustacean.

With 2 softgels of Omega 3 Krill Oil you take in 260 mg/day of EPA and DHA, and their bioavailability is up to 4 times higher than that of Omega 3s derived from fish28.

What’s more, Omega 3 Krill Oil leaves no fishy aftertaste.

Omega 3s are valuable antioxidants29 that are also useful for counteracting tiredness because they:

• support brain activity by protecting the nervous system (250 mg/day DHA)30
• regulate fat metabolism, providing more energy.31

Do you want to get energy naturally? You can do just that thanks to the active ingredients of Energea+ New Formula!

Its formulation is free from caffeine and nervous system stimulants. Thanks to its ingredients, Spirulina1, Ashwagandha2, Royal Jelly3, Ginseng4, Grape Seed5 and Manganese6, your body will be able to produce new energy and face each day with grit and determination!

This is precisely what sets it apart from other products on the market: the ingredients of Energea+ New Formula don’t drain what little energy you have left by further stimulating your already overstretched nervous system; instead, they act on the mitochondria2, our “energy powerhouses”.

To counteract physical and mental tiredness, you can pair it with Organic Aronia Juice, made exclusively from organic Aronia berries: nothing more, nothing less.

Aronia is a fruit rich in antioxidants, polyphenols and vitamin C, biochemical compounds that are extremely important for supporting body and mind32.

Supplements for physical tiredness

If you love sport and want to maximise your performance, or you put your body through significant physical exertion every day, we have created two winning formulas for you: Sport 1 Endurance and Sport 2 Recupero.

Sport 1 Endurance

With natural dry extracts of Damiana, Suma, Cordyceps and Eleutherococcus, you withstand the fatigue that comes from physical exertion and protect the wellbeing of your muscles:

• With Suma33 you support sugar metabolism.
• Thanks to Eleutherococcus34 you have greater endurance during prolonged physical exertion.
• Damiana and Cordyceps35 provide adaptogenic and tonic properties.

Put simply, you have physical stamina, you support your sports performance and you stay focused on your goal during your training sessions.

The Sport 1 Endurance formulation can support you both during physical activity and during rest periods, so that you maintain the benefits over the long term.

Sport 2 Recupero

It needs no introduction: Sport 2 Recupero is formulated to support muscle recovery, and the body’s recovery in general, after the most intense physical activity.

It is made up of Spirulina36, Maqui37 and Pomegranate38, as well as Elderberry and Grape Seed.

Spirulina is a freshwater alga (iodine-free) that provides proteins of high biological value36, to support and nourish the muscles.

Sport 2 Recupero also supports you thanks to the Maqui37 and Pomegranate38 in its formulation, two fruits with high antioxidant activity, which are needed to neutralise the toxins that build up when the body is subjected to intense exertion or activity.

Supplements for chronic tiredness

Tiredness can even be a “friend”.

In fact, if you listen to your body, you’ll realise that tiredness is simply a physiological response: your body is asking for rest so that it can regenerate.

When you ignore these signals, or simply aren’t able to heed them, chronic tiredness sets in: a condition that seems impossible to escape.

What matters in these cases is not to overload the nervous system and to give our body the right nutrients it needs to overcome the constant challenges of daily life, as well as proper rest.

Energea+ New Formula is the supplement with specific active ingredients to provide energy and vitality.

Made with Spirulina1, Ashwagandha2, Royal Jelly3, Ginseng4, Grape Seed5 and Manganese6, this formulation can support your energy levels without further stimulating your already overloaded nervous system. Indeed, Energea+ contains no caffeine.

The active ingredients of Energea+ New Formula support your cells in producing new energy, as they stimulate the activity of organelles such as the mitochondria2, which are the power stations of our body.

Extremely valuable support in cases of chronic tiredness comes from the Glutatione Forte formula, made with Reduced Glutathione and Quercetin, the antioxidants par excellence.

The Glutatione Forte formulation has been specially designed to provide the maximum permitted levels of Reduced Glutathione7 and Quercetin8, together with Naringenin10, OxiP® 12/15 and Selenium11.

Antioxidants are needed to support the body, especially when tiredness has built up, because they neutralise all those harmful substances (e.g. free radicals, toxins, etc.) that can speed up the ageing process in our body.

Thanks to the ingredients of Glutatione Forte:

• you feel stronger and more energetic
• you help your body cleanse itself of toxins
• you support your immune system.

Speaking of the immune system, you can give it extra support when you’re particularly tired, so that your body is always ready to defend itself against attacks by pathogens.

You can pair Glutatione Forte with ImmunoGea, made with Shiitake, Uncaria, Propolis, a postbiotic Lactobacillus, Zinc and Selenium, all from natural sources.

Shiitake, in particular, is a mushroom that has been used for thousands of years in Traditional Medicine, and Salugea selected it for its content of beta-glucans, substances that are useful for their positive action on the immune system39.

In the ImmunoGea formula you’ll also find a postbiotic Lactobacillus, which has been shown40 to promote the activity of plasmacytoid dendritic cells (pDCs), a particular subset of immune cells that act as promoters of the immune system.

Extra help also comes from our liquid supplements, such as Organic Acerola Juice.

Acerola, the only ingredient in our Juice, is one of the fruits richest in Vitamin C, an ally of the immune system and of wellbeing in general41.

In fact, Vitamin C is also a valuable support in counteracting fatigue and tiredness.

What’s more, taking Vitamin C of natural origin, such as the Vitamin C you’ll find in Organic Acerola Juice, allows for its optimal absorption by the body, unlike synthetic Vitamin C42.

Supplements for seasonal changes and tiredness

Tiredness usually creeps in along with the new season, as a result of the effort our body has to make to adapt to changes in temperature and light. At these times, it becomes extremely important to focus on detoxifying the body, to support it in eliminating the toxins that can build up and cause further tiredness and fatigue, typical signs of the change of season.

Meet Epasal, the supplement made with Artichoke43, Phyllanthus44, Milk Thistle45, Fumitory46 and Olivattiva®47, with specific properties to support liver activity.

As we all know, the liver is the “filter” organ of our body, responsible for cleansing the blood of all waste substances, as well as being the site of important biological processes such as the metabolism of sugars and fats, the secretion of digestive substances, the production of cholesterol and much more besides.

So, if your liver works well, your whole body works well!

The active ingredients of Epasal protect the liver and its cells in general and, in particular:

• support the metabolism of sugars and fats,
• promote digestion.

To support the liver, we pair Epasal with Glutatione Forte.

Thanks to the powerful antioxidants it provides, such as reduced Glutathione7, Quercetin8 and Naringenin10, you support the liver’s cleansing action and your whole body’s ability to counter free radicals.

When the seasons change, do you feel like sleeping all day, and is leaving your pillow behind in the morning a real struggle?

To wake up full of vitality and keep your energy levels high all day long, the active ingredients of Energea+ New Formula, Salugea’s energising supplement, come to your rescue.

Without caffeine, you increase your energy reserves naturally and don’t subject your nervous system to further stimulation.

Energea+ is made with Spirulina1, Ashwagandha2, Royal Jelly3, Ginseng4, Grape Seed5 and Manganese6, natural plant extracts that nourish your cells and promote the production of new energy.

Notes and bibliography

1 Lupatini AL, Colla LM, Canan C, Colla E. Potential application of microalga Spirulina platensis as a protein source. J Sci Food Agric. 2017 Feb;97(3):724-732. doi: 10.1002/jsfa.7987. Epub 2016 Sep 12. PMID: 27507218.

2 Lee DH, Ahn J, Jang YJ, et al. Withania somnifera Extract Enhances Energy Expenditure via Improving Mitochondrial Function in Adipose Tissue and Skeletal Muscle. Nutrients. 2020;12(2):431. Published 2020 Feb 7. doi:10.3390/nu12020431

3 Morita H, Ikeda T, Kajita K, Fujioka K, Mori I, Okada H, Uno Y, Ishizuka T. Effect of royal jelly ingestion for six months on healthy volunteers. Nutr J. 2012 Sep 21;11:77. doi: 10.1186/1475-2891-11-77. PMID: 22995464; PMCID: PMC3499288

4 Kim HG, Cho JH, Yoo SR, Lee JS, Han JM, Lee NH, Ahn YC, Son CG. Antifatigue effects of Panax ginseng C.A. Meyer: a randomised, double-blind, placebo-controlled trial. PLoS One. 2013 Apr 17;8(4):e61271. doi: 10.1371/journal.pone.0061271. PMID: 23613825; PMCID: PMC3629193

5 Belviranlı M, Gökbel H, Okudan N, Başaralı K. Effects of grape seed extract supplementation on exercise-induced oxidative stress in rats. Br J Nutr. 2012 Jul;108(2):249-56. doi: 10.1017/S0007114511005496. Epub 2011 Oct 20. PMID: 22011589

6 Chen P, Bornhorst J, Aschner M. Manganese metabolism in humans. Front Biosci (Landmark Ed). 2018 Mar 1;23:1655-1679. doi: 10.2741/4665. PMID: 29293455

7 Pizzorno J. Glutathione! Integr Med (Encinitas). 2014 Feb;13(1):8-12. PMID: 26770075; PMCID: PMC4684116

8 Oxid Med Cell Longev. 2016. Mechanisms of Neuroprotection by Quercetin: Counteracting Oxidative Stress and More. Costa LG, Garrick JM, Roquè PJ, Pellacani C.

9 Richie JP Jr, Nichenametla S, Neidig W, Calcagnotto A, Haley JS, Schell TD, Muscat JE. Randomized controlled trial of oral glutathione supplementation on body stores of glutathione. Eur J Nutr. 2015 Mar;54(2):251-63. doi: 10.1007/s00394-014-0706-z. Epub 2014 May 5. PMID: 24791752.

10 Zaidun NH, Thent ZC, Latiff AA. Combating oxidative stress disorders with citrus flavonoid: Naringenin. Life Sci. 2018 Sep 1;208:111-122. doi: 10.1016/j.lfs.2018.07.017. Epub 2018 Aug 10. PMID: 30021118

11 Brenneisen P, Steinbrenner H, Sies H. Selenium, oxidative stress, and health aspects. Mol Aspects Med. 2005 Aug-Oct;26(4-5):256-67. doi: 10.1016/j.mam.2005.07.004. PMID: 16105679.

12 Lietti A, Cristoni A, Picci M. Studies on Vaccinium myrtillus anthocyanosides. I. Vasoprotective and antiinflammatory activity. Arzneimittelforschung. 1976;26(5):829-32. PMID: 9100 - Lietti A, Cristoni A, Picci M. Studies on Vaccinium myrtillus anthocyanosides. I. Vasoprotective and antiinflammatory activity. Arzneimittelforschung. 1976;26(5):829-32. PMID: 9100

12 Song N, Jia L, Cao H, Ma Y, Chen N, Chen S, Lv X, Yang G. Gypenoside Inhibits Endothelial Cell Apoptosis in Atherosclerosis by Modulating Mitochondria through PI3K/Akt/Bad Pathway. Biomed Res Int. 2020 Jun 20;2020:2819658. doi: 10.1155/2020/2819658. PMID: 32685460; PMCID: PMC7327587

12 Liao H, Ye J, Gao L, Liu Y. The main bioactive compounds of Scutellaria baicalensis Georgi. for alleviation of inflammatory cytokines: A comprehensive review. Biomed Pharmacother. 2021 Jan;133:110917. doi: 10.1016/j.biopha.2020.110917. Epub 2020 Nov 17. PMID: 33217688

12 Ghanim H, Sia CL, Abuaysheh S, Korzeniewski K, Patnaik P, Marumganti A, Chaudhuri A, Dandona P. An antiinflammatory and reactive oxygen species suppressive effects of an extract of Polygonum cuspidatum containing resveratrol. J Clin Endocrinol Metab. 2010 Sep;95(9):E1-8. doi: 10.1210/jc.2010-0482. Epub 2010 Jun 9. PMID: 20534755; PMCID: PMC2936054

13 Song N, Jia L, Cao H, Ma Y, Chen N, Chen S, Lv X, Yang G. Gypenoside Inhibits Endothelial Cell Apoptosis in Atherosclerosis by Modulating Mitochondria through PI3K/Akt/Bad Pathway. Biomed Res Int. 2020 Jun 20;2020:2819658. doi: 10.1155/2020/2819658. PMID: 32685460; PMCID: PMC7327587

14 Liao H, Ye J, Gao L, Liu Y. The main bioactive compounds of Scutellaria baicalensis Georgi. for alleviation of inflammatory cytokines: A comprehensive review. Biomed Pharmacother. 2021 Jan;133:110917. doi: 10.1016/j.biopha.2020.110917. Epub 2020 Nov 17. PMID: 33217688

15 Ghanim H, Sia CL, Abuaysheh S, Korzeniewski K, Patnaik P, Marumganti A, Chaudhuri A, Dandona P. An antiinflammatory and reactive oxygen species suppressive effects of an extract of Polygonum cuspidatum containing resveratrol. J Clin Endocrinol Metab. 2010 Sep;95(9):E1-8. doi: 10.1210/jc.2010-0482. Epub 2010 Jun 9. PMID: 20534755; PMCID: PMC2936054

16 Amagase H, Nance DM. A randomized, double-blind, placebo-controlled, clinical study of the general effects of a standardized Lycium barbarum (Goji) Juice, GoChi. J Altern Complement Med. 2008;14(4):403-412. doi:10.1089/acm.2008.0004

17 Skenderidis P, Leontopoulos S, Lampakis D. Goji Berry: Health Promoting Properties. Nutraceuticals. 2022; 2(1):32-48. https://doi.org/10.3390/nutraceuticals2010003.

18 Ma ZF, Zhang H, Teh SS, et al. Goji Berries as a Potential Natural Antioxidant Medicine: An Insight into Their Molecular Mechanisms of Action. Oxid Med Cell Longev. 2019;2019:2437397. Published 2019 Jan 9. doi:10.1155/2019/2437397

19 Calabrese C, Gregory WL, Leo M, Kraemer D, Bone K, Oken B. Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial. J Altern Complement Med. 2008;14(6):707-713. doi:10.1089/acm.2008.0018

20 Lin H, Zhang X, Liu J, Yuan L, Liu J, Wang C, Sun J, Chen J, Jing S, Li H. Schisantherin A improves learning and memory abilities partly through regulating the Nrf2/Keap1/ARE signaling pathway in chronic fatigue mice. Exp Ther Med. 2021 Apr;21(4):385. doi: 10.3892/etm.2021.9816. Epub 2021 Feb 23. PMID: 33680107; PMCID: PMC7918174

21 Sanodiya BS, Thakur GS, Baghel RK, Prasad GB, Bisen PS. Ganoderma lucidum: a potent pharmacological macrofungus. Curr Pharm Biotechnol. 2009 Dec;10(8):717-42. doi: 10.2174/138920109789978757. PMID: 19939212

22 Cropley M, Banks AP, Boyle J. The Effects of Rhodiola rosea L. Extract on Anxiety, Stress, Cognition and Other Mood Symptoms. Phytother Res. 2015 Dec;29(12):1934-9. doi: 10.1002/ptr.5486. Epub 2015 Oct 27. PMID: 26502953

23 Wattanathorn J, Mator L, Muchimapura S, Tongun T, Pasuriwong O, Piyawatkul N, Yimtae K, Sripanidkulchai B, Singkhoraard J. Positive modulation of cognition and mood in the healthy elderly volunteer following the administration of Centella asiatica. J Ethnopharmacol. 2008 Mar 5;116(2):325-32. doi: 10.1016/j.jep.2007.11.038. Epub 2007 Dec 4. PMID: 18191355

24 2011 Jul 15;18(10):848-51. doi: 10.1016/j.phymed.2011.01.016. Epub 2011 Feb 25. Anxiolytic-like effect of Griffonia simplicifolia Baill. seed extract in rats G Carnevale, V Di Viesti, M Zavatti, P Zanoli

25 2017 Apr;18(2):263-273. doi: 10.1007/s10522-017-9686-8. Epub 2017 Mar 1. Jujube (Ziziphus Jujuba Mill.) fruit feeding extends lifespan and increases tolerance to environmental stresses by regulating aging-associated gene expression in Drosophila Saurav Ghimire, Man Su Kim

26 Pilot trial of Melissa officinalis L. leaf extract in the treatment of volunteers suffering from mild-to-moderate anxiety disorders and sleep disturbances. Cases J, Ibarra A, Feuillère N, Roller M, Sukkar SG. Med J Nutrition Metab. 2011 Dec;4(3):211-218. Epub 2010 Dec 17

27 Curr Med Chem . 2018;25(37):4854-4865. doi: 10.2174/0929867323666160919095519. Phytochemical and Pharmacological Activity Profile of Crataegus oxyacantha L. (Hawthorn) - A Cardiotonic Herb Ilkay Erdogan Orhan

28 Köhler A, Sarkkinen E, Tapola N, Niskanen T, Bruheim I. Bioavailability of fatty acids from krill oil, krill meal and fish oil in healthy subjects–a randomized, single-dose, cross-over trial. Lipids Health Dis. 2015 Mar 15;14:19. doi: 10.1186/s12944-015-0015-4. PMID: 25884846; PMCID: PMC4374210

29 Fassett RG, Coombes JS. Astaxanthin, oxidative stress, inflammation and cardiovascular disease. Future Cardiol. 2009;5(4):333-342. doi:10.2217/fca.09.19

30 Konagai C, Yanagimoto K, Hayamizu K, Han L, Tsuji T, Koga Y. Effects of krill oil containing n-3 polyunsaturated fatty acids in phospholipid form on human brain function: a randomized controlled trial in healthy elderly volunteers. Clin Interv Aging. 2013;8:1247-57. doi: 10.2147/CIA.S50349. Epub 2013 Sep 19. PMID: 24098072; PMCID: PMC3789637

31 Ursoniu S, Sahebkar A, Serban MC, Antal D, Mikhailidis DP, Cicero A, Athyros V, Rizzo M, Rysz J, Banach M; Lipid and Blood Pressure Meta-analysis Collaboration Group. Lipid-modifying effects of krill oil in humans: systematic review and meta-analysis of randomized controlled trials. Nutr Rev. 2017 May 1;75(5):361-373. doi: 10.1093/nutrit/nuw063. PMID: 28371906

32 Ren Y, Frank T, Meyer G, Lei J, Grebenc JR, Slaughter R, Gao YG, Kinghorn AD. Potential Benefits of Black Chokeberry (Aronia melanocarpa) Fruits and Their Constituents in Improving Human Health. Molecules. 2022 Nov 13;27(22):7823. doi: 10.3390/molecules27227823. PMID: 36431924; PMCID: PMC9696386.

33 Mendes FR, Carlini EA. Brazilian plants as possible adaptogens: an ethnopharmacological survey of books edited in Brazil. J Ethnopharmacol. 2007 Feb 12;109(3):493-500. doi: 10.1016/j.jep.2006.08.024. Epub 2006 Sep 1. PMID: 17030478

34 Huang LZ, Huang BK, Ye Q, Qin LP. Bioactivity-guided fractionation for anti-fatigue property of Acanthopanax senticosus. J Ethnopharmacol. 2011 Jan 7;133(1):213-9. doi: 10.1016/j.jep.2010.09.032. PMID: 20920564

35 Rossi P, Buonocore D, Altobelli E, Brandalise F, Cesaroni V, Iozzi D, Savino E, Marzatico F. Improving Training Condition Assessment in Endurance Cyclists: Effects of Ganoderma lucidum and Ophiocordyceps sinensis Dietary Supplementation. Evid Based Complement Alternat Med. 2014;2014:979613. doi: 10.1155/2014/979613. Epub 2014 Apr 1. PMID: 24799948; PMCID: PMC3995149

36 Med Sci Sports Exerc. 2010 Jan;42(1):142-51. doi:10.1249/MSS.0b013e3181ac7a45. Ergogenic and antioxidant effects of spirulina supplementation in humans. Kalafati M, Jamurtas AZ, Nikolaidis MG, Paschalis V, Theodorou AA, Sakellariou GK, Koutedakis Y, Kouretas D.

37 Romanucci V, D'Alonzo D, Guaragna A, Di Marino C, Davinelli S, Scapagnini G, Di Fabio G, Zarrelli A. Bioactive Compounds of Aristotelia chilensis Stuntz and their Pharmacological Effects. Curr Pharm Biotechnol. 2016;17(6):513-23. doi: 10.2174/1389201017666160114095246. PMID: 26778456

38 Shaygannia E, Bahmani M, Zamanzad B, Rafieian-Kopaei M. A Review Study on Punica granatum L. J Evid Based Complementary Altern Med. 2016 Jul;21(3):221-7. doi: 10.1177/2156587215598039. Epub 2015 Jul 30. PMID: 26232244.

39 Novak M, Vetvicka V. Beta-glucans, history, and the present: immunomodulatory aspects and mechanisms of action. J Immunotoxicol. 2008 Jan;5(1):47-57. doi: 10.1080/15476910802019045. PMID: 18382858.

40 Takeo Shibata, et al. Lactococcus lactis JCM5805 activates anti-viral immunity and reduces symptoms of common cold and influenza in healthy adults in a randomized controlled trial, Journal of Functional Foods, Volume 24, 2016, Pages 492-500, ISSN 1756-4646, https://doi.org/10.1016/j.jff.2016.03.035. (https://www.sciencedirect.com/science/article/pii/S175646461630072X).

41 Prakash A, Baskaran R. Acerola, an untapped functional superfruit: a review on latest frontiers. J Food Sci Technol. 2018;55(9):3373-3384. doi:10.1007/s13197-018-3309-5

42 Clardy J, Walsh C. Lessons from natural molecules. Nature. 2004 Dec 16;432(7019):829-37. doi: 10.1038/nature03194. PMID: 15602548.

43 Ben Salem M, Affes H, Ksouda K, Dhouibi R, Sahnoun Z, Hammami S, Zeghal KM. Pharmacological Studies of Artichoke Leaf Extract and Their Health Benefits. Plant Foods Hum Nutr. 2015 Dec;70(4):441-53. doi: 10.1007/s11130-015-0503-8. PMID: 26310198

44 Lee NY, Khoo WK, Adnan MA, Mahalingam TP, Fernandez AR, Jeevaratnam K. The pharmacological potential of Phyllanthus niruri. J Pharm Pharmacol. 2016 Aug;68(8):953-69. doi: 10.1111/jphp.12565. Epub 2016 Jun 10. PMID: 27283048

45 Hackett ES, Twedt DC, Gustafson DL. Milk thistle and its derivative compounds: a review of opportunities for treatment of liver disease. J Vet Intern Med. 2013 Jan-Feb;27(1):10-6. doi: 10.1111/jvim.12002. Epub 2012 Nov 9. PMID: 23140176

46 Aktay G, Deliorman D, Ergun E, Ergun F, Yeşilada E, Cevik C. Hepatoprotective effects of Turkish folk remedies on experimental liver injury. J Ethnopharmacol. 2000 Nov;73(1-2):121-9. doi: 10.1016/s0378-8741(00)00286-5. PMID: 11025147

47 Barbaro B, Toietta G, Maggio R, Arciello M, Tarocchi M, Galli A, Balsano C. Effects of the olive-derived polyphenol oleuropein on human health. Int J Mol Sci. 2014 Oct 14;15(10):18508-24. doi: 10.3390/ijms151018508. PMID: 25318054; PMCID: PMC4227229