Antioxidant

Glutatione Forte

Contenuto: 60 Acid-resistant Vegetable Capsules

"Even before finishing the first pack, I noticed a clear improvement: more energy, detoxification of the liver and the gut." - Chiara

With Reduced Glutathione and Quercetin at the maximum daily intake, Naringenin, OxiP® with antioxidant action, and Selenium, which contributes to the normal function of the immune system.

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Glutathione, Quercetin and Naringenin Supplement

Glutatione Forte is the first supplement to combine in a single product Reduced Glutathione and Quercetin at the maximum daily intake, as well as Naringenin, Selenium and OxiP®, a registered blend of natural active ingredients with a powerful antioxidant action.

A truly innovative supplement!

To date, it is the only product on the market with these characteristics.

With Glutatione Forte you have at your disposal ingredients with an antioxidant action that are one of a kind. This means detoxification from toxins, immune support, energy and vitality, protection of your organs, heart and circulation, and many other benefits.

 

 

Protected in pharmaceutical-grade dark glass bottles. Glass is the only material that can guarantee the quality and safety of the product over time, right down to the last capsule!

No colourings, preservatives or sweeteners.

A new-generation 100% natural product whose active ingredients come from biofermentation and 100% natural sources, not from a laboratory. What’s more, the active ingredients of Glutatione Forte work in synergy, enhancing one another. For an even more marked and long-lasting effect.

Having a product obtained from natural sources is a guarantee of high quality and assimilation. Studies1-2 show, in fact, that a product obtained from natural sources is assimilated better by our body than those created in a laboratory (synthetic).

Who this Glutathione, Quercetin and Naringenin formula is for

The Glutatione Forte formula is suitable for those who:

  • Want a Reduced Glutathione supplement obtained from natural sources (biofermentation);
  • Are looking for a product that also contains Quercetin and Naringenin;
  • Want the maximum daily intake of each active ingredient for better effectiveness;
  • Feel tired, worn out and drained after a period of convalescence;
  • Do sport and want to support their energy;
  • Are highly exposed to environmental pollutants;
  • Are going through a period of stress;
  • Have an irregular diet, smoke or drink alcohol;
  • Have finished a course of medication.

benefits of glutathione

The benefits you get from Glutatione Forte

Thanks to the 100% natural active ingredients of Glutatione Forte:

  • You take Glutathione, Quercetin and Naringenin in a single dose
  • You take in antioxidants, which are precious for your body
  • You cleanse your body of free radicals and toxins
  • You support the immune system
  • Your hair and nails benefit too
  • You feel more energetic
  • You promote muscle function
  • You protect your heart and circulation
  • You counter oxidative stress

Why Glutatione Forte is different from other Reduced Glutathione or Quercetin supplements

  • Because it contains Reduced Glutathione (not liposomal) together with Quercetin and Naringenin in a single product.
  • It comes in acid-resistant capsules.
  • It is enclosed in dark glass bottles of pharmaceutical grade. Glass is the only material that can guarantee the quality and safety of the product over time, right down to the last capsule!
  • It combines in a single product Reduced Glutathione, Quercetin (at the maximum daily intake!) and Naringenin.
  • It also provides Selenium and OxiP®, a registered blend of active ingredients with a powerful antioxidant action.
  • Its active ingredients come from biofermentation and 100% natural sources (and not from a laboratory).
  • It has an innovative formulation.
  • It is suitable for vegans and vegetarians.
  • It contains no gluten or lactose.

Liposomal or reduced Glutathione? Let’s clear things up

 

 

How Glutatione Forte, the Glutathione and Quercetin supplement, works

Glutatione Forte combines in a single product Reduced Glutathione and Quercetin at the maximum daily intake, as well as Naringenin, Selenium and OxiP® (a registered blend of natural active ingredients with a powerful antioxidant action).

Reduced Glutathione for a supply of antioxidants

Glutathione is a natural protein substance made up of three amino acids: glycine, cysteine and glutamic acid. It is considered the king of endogenous antioxidants (those produced by our own body)3. It protects the body and the liver and supports the liver in its work of neutralising toxins, both those produced by our own body and those that come from external agents4. Its function is therefore twofold: “protective” and “detoxifying”.

Glutathione is a fundamental element that is produced naturally by the liver but, unfortunately, often in quantities that are insufficient to meet our need for this substance. That is why we need to supplement it. According to many studies, glutathione is also linked to the immune system, in particular through an immunomodulating action that helps regulate the response of the immune defences. We will look at this aspect in more depth in the “Experimental Phytotherapy” section.

Quercetin for natural protection

Obtained from the Caper plant. The Caper is the plant that contains the highest percentage of natural Quercetin5. Many studies have shown that Quercetin is particularly useful for protecting the cells of the heart (those of the heart muscle), limiting the toxicity of certain pharmacological and other agents6 (for example cyclophosphamide, cisplatin, ciprofloxacin, manganese, cadmium, arsenic), supporting the functions of the lungs and joints and helping to balance blood pressure. All these aspects are supported by clinical studies that you can consult in the section dedicated to Experimental Phytotherapy.

Naringenin to support the immune system

Obtained from the fruit of the Chinotto. The Chinotto is a citrus fruit native to southern China (hence its common name) that only spread to the Italian peninsula in the 6th–7th century AD. Its origin is uncertain: it is probably a genetic evolution, through spontaneous selection, of the bitter orange. Naringenin (a flavanone) is one of the main active constituents naturally present in chinotto and gives it its typical bitter taste. Several studies have shown the positive action of this molecule on the immune system, as an antioxidant and in the proper metabolism of sugars and lipids. All these aspects, and others, are supported by clinical studies that you can consult in the Experimental Phytotherapy section.

OxiP® with a powerful antioxidant action

A registered blend of active ingredients with a powerful antioxidant action. In particular, it contains:

  • Bilberry: rich in Anthocyanins, antioxidant substances useful for the skin, circulation, vein walls, eyesight, microcirculation and lung tissue.
  • Gynostemma: an adaptogenic plant able to increase the body’s resistance to stress. It contains saponins (around 80 different ones), flavonoids, polysaccharides, amino acids and trace elements useful for supporting the functions of the heart and circulation.
  • Scutellaria: useful for supporting and modulating the immune system.
  • Fallopia (or Polygonum cuspidatum): a plant extremely rich in Resveratrol. Fallopia is an excellent plant for its tonic and invigorating action.

The characteristics mentioned are supported by scientific studies, explored in more depth in the Experimental Phytotherapy section.

Selenium for the proper functioning of antioxidant mechanisms

A mineral trace element that allows the antioxidant mechanisms inside cells to work properly. Selenium is a cofactor of dozens of proteins, which for this very reason are known as selenoproteins. It also takes part in several other fundamental processes, from DNA synthesis to the metabolism of thyroid hormones, by way of antioxidant protection and reproduction. It is also excellent as immune support (more details in the Experimental Phytotherapy section).

technical details

To get the most benefit we recommend taking two capsules of Glutatione Forte a day.

In particular:

  • Mid-morning, away from meals: one capsule of Glutatione Forte
  • Mid-afternoon, away from meals: one capsule of Glutatione Forte

Glutatione Forte comes in acid-resistant capsules: for this reason we recommend taking it at least two hours away from your main meals.

Length of the course with Glutatione Forte

You will already notice the benefits after the first few doses.

We recommend carrying on with the course for three months to stabilise the results achieved.

At the end of the course, give us a call! We are interested in you and we want to know how you got on. Together with our experts you will work out how to approach the following period so as to maintain the results obtained!

On its own the Glutatione Forte formula already gives you excellent results. If you want to make its action even more complete you can combine it with the formulas of:

  • Epasal, to purify the liver and, in general, the body;
  • Pausanorm Forte, for the wellbeing of women in menopause, in particular for the skin;
  • DKE + Magnesio: to support the immune defences and supplement natural vitamin D;
  • Sanaos New Formula, to keep joints and ligaments young and strong;
  • Kiomasal, for the beauty of skin, hair and nails;
  • Sport 1 Endurance and Sport 2 Recupero, to support sports activity at every stage;
  • Organic Goji Juice or Organic Maqui: to increase the supply of antioxidants.

Warnings

Food supplements are not intended as a substitute for a varied and balanced diet and a healthy lifestyle. Keep out of the reach of children under 3 years of age. Do not exceed the recommended daily dose. The expiry date shown refers to the product when intact and stored in a cool, dry place, away from sources of light and heat.

characteristics of Glutatione Forte Salugea

Caper (Capparis spinosa L.) fruit d.e. std. 50% quercetin, reduced L-Glutathione from bio-fermentation (23.3%), Acid-resistant capsule (coating agent: hydroxypropyl methylcellulose; gelling agent: gellan gum), Chinotto (Citrus myrtifolia Raf.) fruit d.e. std. 40% naringenin, OxiP® (Vaccinium myrtillus L. fruit, Gynostemma pentaphyllum (Thunb.) Makino herb, Scutellaria baicalensis Georgi root, Fallopia japonica (Houtt.) Ronse Dec. root) d.e. std. 1% anthocyanins - 1% gypenosides - 1% baicalin - 0.7% resveratrol, Selenium L-Methionine, Silica from Bamboo shoots, Anti-caking agents: Vegetable magnesium stearate. The dry extracts are carried on maltodextrins, acacia fibre and rice proteins.

Nutritional Values

AVERAGE INTAKE OF NUTRIENTS AND VEGETABLE EXTRACTS PER DAILY DOSE (2 Capsules)

Caper d.e. std.

400 mg

of which Quercetin

200 mg

Reduced Glutathione

250 mg

Chinotto d.e. std.

150 mg

of which Naringenin

60 mg

OxiP®

60 mg

of which Total Anthocyanins

0.6 mg

of which Total Gypenosides

0.6 mg

of which Baicalin

0.6 mg

of which Resveratrol

0.4 mg

Selenium

55 µg*

*100% NRV

Glutatione Forte was created to bring to market an innovative product that would combine, for the very first time, Reduced Glutathione, Quercetin (at the maximum daily intake) and Naringenin. A truly innovative supplement on the market!

Every component of Glutatione Forte comes from biofermentation and 100% natural sources, and not from a laboratory, as is the case with most products on the market.

It also provides Selenium and OxiP®, a registered blend of active ingredients with a powerful antioxidant action.

Lastly, Glutatione Forte comes in acid-resistant capsules.

Using this type of capsule ensures complete protection of GSH from breakdown in the stomach, so that it is as available as possible for absorption and to perform its function.

Experimental Phytotherapy

Reduced Glutathione

  • Haddad JJ, Safieh-Garabedian B, Saadé NE, Land SC. Thiol regulation of pro-inflammatory cytokines reveals a novel immunopharmacological potential of glutathione in the alveolar epithelium. J Pharmacol Exp Ther. 2001 Mar;296(3):996-1005. PMID: 11181934.

In this study, the researchers focused on the anti-inflammatory properties of glutathione in the pulmonary alveoli. To do this, they grew an in vitro model of alveolar epithelial cells and challenged them with pro-inflammatory cytokines. They then introduced reduced glutathione and observed that it reduces the production and release of pro-inflammatory cytokines. The researchers suggest that these positive results could also apply to the in vivo treatment of lung disorders.

  • Polonikov A. Endogenous Deficiency of Glutathione as the Most Likely Cause of Serious Manifestations and Death in COVID-19 Patients. ACS Infect Dis. 2020 Jul 10;6(7):1558-1562. doi: 10.1021/acsinfecdis.0c00288. Epub 2020 May 28. PMID: 32463221; PMCID: PMC7263077.

This study assessed glutathione deficiency in relation to the most severe manifestations in patients with COVID-19 and went on to show how the use of glutathione could be a means of treating (under medical supervision) and preventing COVID-19.

  • Fraternale A, Paoletti MF, Casabianca A, Oiry J, Clayette P, Vogel JU, Cinatl J Jr, Palamara AT, Sgarbanti R, Garaci E, Millo E, Benatti U, Magnani M. Antiviral and immunomodulatory properties of new pro-glutathione (GSH) molecules. Curr Med Chem. 2006;13(15):1749-55. doi: 10.2174/092986706777452542. PMID: 16787218.

In this review, the researchers highlighted how glutathione deficiency is the common denominator of various diseases, viral infections and immune dysfunctions. Conversely, Reduced Glutathione intake has proved useful in inhibiting viral replication, inhibiting the production of pro-inflammatory cytokines and supporting the treatment of allergies.

Quercetin

  • Oxid Med Cell Longev. 2016. Mechanisms of Neuroprotection by Quercetin: Counteracting Oxidative Stress and More. Costa LG, Garrick JM, Roquè PJ, Pellacani C.
  • Molecules. 2019 Mar 21. Antioxidant Activities of Quercetin and Its Complexes for Medicinal Application. Xu D, Hu MJ, Wang YQ, Cui YL.

These studies showed that Quercetin: acts as a scavenger of radicals derived from oxygen and nitrogen, i.e. it is able to convert these species into non-radical compounds that are free of toxicity; activates the transcription factor Nrf2, which promotes the expression of a wide range of antioxidant genes; increases the expression of PON2, an enzyme that protects cells from oxidative damage; induces the synthesis of glutathione, a powerful antioxidant; increases the expression of antioxidant enzymes, including superoxide dismutase, catalase, glutathione peroxidase and haem oxygenase.

  • Nutrients 2016 Mar 15. Quercetin, Inflammation and Immunity. Li Y, Yao J, Han C, Yang J, Chaudhry MT, Wang S, Liu H, Yin Y.

In this study, the researchers showed that quercetin is a cofactor of many intracellular signalling kinases, phosphatases, enzymes and membrane proteins, and that it also has powerful anti-inflammatory and immunostimulant properties.

Naringenin

  • Nutraceutical Value of Citrus Flavanones and Their Implications in Cardiovascular Disease. Testai L, Calderone V. Nutrients. 2017 May 16;9(5). Review.

In this review, the researchers summarised the research linking naringenin to the incidence of cardiovascular disease. In particular, the various epidemiological studies showed that fruits of the genus Citrus significantly reduce the risk of cardiovascular disease.

  • Da Pozzo E, Costa B, Cavallini C, Testai L, Martelli A, Calderone V, Martini C. The Citrus Flavanone Naringenin Protects Myocardial Cells against Age-Associated Damage. Oxid Med Cell Longev. 2017;2017:9536148. doi: 10.1155/2017/9536148. Epub 2017 Mar 12. PMID: 28386313; PMCID: PMC5366223.

In this study, the researchers showed that naringenin has protective properties against cardiometabolic disorders. In particular, the results suggested that naringenin has beneficial and protective anti-ageing effects on myocardial cells.

  • Zeng W, Jin L, Zhang F, Zhang C, Liang W. Naringenin as a potential immunomodulator in therapeutics. Pharmacol Res. 2018 Sep;135:122-126. doi: 10.1016/j.phrs.2018.08.002. Epub 2018 Aug 3. PMID: 30081177.

In this study, the researchers focused on naringenin’s ability to inhibit the inflammatory response in different types of cells. According to the scientists, this property is due to naringenin’s ability to suppress the production of inflammatory cytokines at a much deeper level than other compounds such as curcumin and apigenin. This is why, the researchers suggest, naringenin is useful as an immunomodulator and in the treatment of related inflammatory diseases.

OxiP®

Bilberry
  • Lietti A, Cristoni A, Picci M. Studies on Vaccinium myrtillus anthocyanosides. I. Vasoprotective and antiinflammatory activity. Arzneimittelforschung. 1976;26(5):829-32. PMID: 9100.

In this animal study, the researchers highlighted the marked anti-inflammatory and antioxidant properties of Bilberry, which help support the proper functioning of many of the body’s systems and structures.

Gynostemma pentaphyllum
  • Song N, Jia L, Cao H, Ma Y, Chen N, Chen S, Lv X, Yang G. Gypenoside Inhibits Endothelial Cell Apoptosis in Atherosclerosis by Modulating Mitochondria through PI3K/Akt/Bad Pathway. Biomed Res Int. 2020 Jun 20;2020:2819658. doi: 10.1155/2020/2819658. PMID: 32685460; PMCID: PMC7327587.

In this study, the researchers looked at Gynostemma in relation to atherosclerosis, currently one of the most frequent causes of illness and death worldwide. In atherosclerosis, the deterioration of endothelial cells is, unfortunately, an important component of the disease. Damage to these cells has knock-on effects on many aspects of vascular function. The research showed that Gynostemma is able to modulate mitochondrial function and consequently enhance endothelial protection.

Scutellaria
  • Liao H, Ye J, Gao L, Liu Y. The main bioactive compounds of Scutellaria baicalensis Georgi. for alleviation of inflammatory cytokines: A comprehensive review. Biomed Pharmacother. 2021 Jan;133:110917. doi: 10.1016/j.biopha.2020.110917. Epub 2020 Nov 17. PMID: 33217688.

In this review of various studies, the researchers focused on Scutellaria’s ability to relieve the discomfort caused by inflammatory cytokines, showing a normalising effect on inflammatory events.

Fallopia
  • Ghanim H, Sia CL, Abuaysheh S, Korzeniewski K, Patnaik P, Marumganti A, Chaudhuri A, Dandona P. An antiinflammatory and reactive oxygen species suppressive effects of an extract of Polygonum cuspidatum containing resveratrol. J Clin Endocrinol Metab. 2010 Sep;95(9):E1-8. doi: 10.1210/jc.2010-0482. Epub 2010 Jun 9. PMID: 20534755; PMCID: PMC2936054.

In this study, the researchers analysed the link between resveratrol, the active ingredient of Fallopia, and oxidative stress and inflammation. Specifically, the resveratrol extract led to a significant reduction in inflammation levels and proved useful in protecting cells from oxidative damage.

  • Ghanim H, Sia CL, Korzeniewski K, Lohano T, Abuaysheh S, Marumganti A, Chaudhuri A, Dandona P. A resveratrol and polyphenol preparation suppresses oxidative and inflammatory stress response to a high-fat, high-carbohydrate meal. J Clin Endocrinol Metab. 2011 May;96(5):1409-14. doi: 10.1210/jc.2010-1812. Epub 2011 Feb 2. PMID: 21289251; PMCID: PMC3085195.

In this study, the researchers showed that resveratrol helps counteract inflammation caused by oxidative stress following meals rich in fats and carbohydrates.

Selenium

  • Kiremidjian-Schumacher L, Roy M. - Selenium and immune function. Z Ernahrungswiss. 1998;37 Suppl 1:50-6. PMID: 9558729.

This research looks at the relationship between Selenium and immune system function. The study was carried out on volunteers, and at the end of the treatment there were improvements in the response of immune cells and therefore in the body’s defences in general.

Bibliography

[1] Thiel RJ. Natural vitamins may be superior to synthetic ones. Med Hypotheses. 2000 Dec;55(6):461-9. doi: 10.1054/mehy.2000.1090. PMID: 11090291.

[2] Clardy J, Walsh C. Lessons from natural molecules. Nature. 2004 Dec 16;432(7019):829-37. doi: 10.1038/nature03194. PMID: 15602548.

[3] Pizzorno J. Glutathione!. Integr Med (Encinitas). 2014;13(1):8-12.

[4] Al-Gubory KH. Environmental pollutants and lifestyle factors induce oxidative stress and poor prenatal development. Reprod Biomed Online. 2014 Jul;29(1):17-31. doi: 10.1016/j.rbmo.2014.03.002. Epub 2014 Mar 21. PMID: 24813750.

[5]Redford, K.E., Abbott, G.W. The ubiquitous flavonoid quercetin is an atypical KCNQ potassium channel activator. Commun Biol 3, 356 (2020). https://doi.org/10.1038/s42003-020-1089-8.

[6] Wang Z, Wang Y, Zhang J, Feng G, Miao S, Lu R, Tian X, Ye Y. Antioxidant Intervention Against Microplastic Hazards. Antioxidants (Basel). 2025 Jun 27;14(7):797. doi: 10.3390/antiox14070797. PMID: 40722901; PMCID: PMC12291741.

Our texts are for information purposes only; they are not to be understood as an indication for the diagnosis and treatment of medical conditions and are in no way intended to replace the advice of a doctor.

Italian Ministry of Health code:  148940

Food supplement: read the warnings on the label.
Food supplements should not be used as a substitute for a varied, balanced diet and a healthy lifestyle.

Confronto

Standard Salugea Standard di mercato
Pharmaceutical-grade dark glass bottle ✓ ❌
High content of active ingredients ✓ ❌
Vegetable capsules ✓ ❌
100% natural and pure ✓ ❌
Standardised dry extracts only ✓ ❌

What you won’t find in our formulations

Our idea of 100% natural also includes what we choose not to use.

No GMOs
No Synthetic Additives
No Plastic
No Artificial Sweeteners
No Lactose
No Synthetic Preservatives

Frequently Asked Questions about the Product

Glutatione Forte can be taken from the age of 12 upwards! If you have any doubts or particular circumstances, we always recommend contacting our Customer Service on 800 688 801.

After the third month of breastfeeding yes, with no problem.

Of course, all Salugea products and programmes can be combined with each other. This way you can work on several needs at the same time. If you have any doubts about taking more than one, contact our experts!

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800-688-801 (Mon-Fri)

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