Hyaluronic Acid Supplement

LuxGea Acido Ialuronico

Contenuto: 60 vegetable capsules


With dual molecular weight Hyaluronic Acid, Vitamin E, Zinc, carotenoids and Vitamin C, which contributes to normal collagen formation for the normal function of the skin.

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Dual molecular weight Hyaluronic Acid supplement for skin hydration

Born from Salugea’s research, LuxGea Acido Ialuronico is the supplement from the LuxGea line with a 100% natural formula featuring Hyaluronic Acid in two different molecular weights (10–100 kDa and 200–600 kDa), Vitamin C from Rosehip, Vitamin E from Sunflower seed, Zinc, Manganese, Silicon from Bamboo, Lutein, Zeaxanthin and Beta-carotene.

A combination of targeted ingredients to support hydration, act on the signs of ageing and promote radiant, naturally toned and smooth-looking skin.

Not all Hyaluronic Acid supplements are the same.

In LuxGea Acido Ialuronico, Hyaluronic Acid comes in two different “sizes”: a smaller form (with a very low molecular weight) and one with a low molecular weight, to support targeted, deep hydration[1].

Molecular weight indicates the “size” of the molecule, an important factor in how much of it the body can actually absorb and use[2].

We can think of Hyaluronic Acid as a natural sponge, able to hold amounts of water far greater than its own weight. It is precisely thanks to this property that it helps keep the skin hydrated and smooth[3].

Over time, however, the amount of Hyaluronic Acid in the skin tends to decrease[4], with effects that can become visible as reduced hydration and firmness and the appearance of wrinkles. This is why supplementing with it may prove helpful.

Every bottle of LuxGea Acido Ialuronico is made of pharmaceutical-grade dark glass, with a reusable safety seal under the cap, for optimal storage of the product, from the first capsule to the last!

The capsules are vegetable-based, for a truly 100% natural product that is suitable for vegans and vegetarians.

Free from colourings, preservatives and synthetic sweeteners.

Who LuxGea Acido Ialuronico is for

Hyaluronic acid, vitamins A-C-E, Carotenoids, Manganese, Zinc and Silicon are the ingredients of LuxGea Acido Ialuronico, helpful for women and men who want:

  • to support skin hydration from within, including in cases of dryness, redness or a feeling of tightness[5];
  • to counter the signs of ageing, such as fine lines and loss of firmness;
  • to promote a toned, radiant and smooth appearance;
  • to support normal collagen formation, thanks to its Vitamin C content;
  • to act on oxidative stress caused by UV rays, smog and environmental factors;
  • to complement their daily skincare routine, or aesthetic medicine or dermatological treatments, with targeted supplementation that supports hydration;
  • a Hyaluronic Acid supplement suitable for vegans and vegetarians;
  • to contribute to the maintenance of normal vision, thanks to its Vitamin A content.

Also suitable for younger people!

Hyaluronic Acid, vitamin A-C-E complex, Carotenoids, Manganese, Zinc and Silicon: the benefits you get from LuxGea Acido Ialuronico

Thanks to the synergy of the ingredients in LuxGea Acido Ialuronico, you get:

  • hyaluronic acid in two different weights (low and very low molecular weight), for a complementary action;
  • support for skin hydration from within;
  • action against the natural decline in Hyaluronic Acid that comes with the passing of time;
  • naturally toned, firm-looking skin;
  • a natural anti-ageing action;
  • action on redness and discomfort caused by a lack of hydration;
  • a high content of active ingredients in a 100% natural formula.

Why choose LuxGea Acido Ialuronico?

  • Formula with patented dual molecular weight Hyaluronic Acid (10–100 kDa and 200–600 kDa).
  • The formula combines the vitamin A-C[6]-E[7] complex, Zinc, Manganese[8], Silicon[9] from Bamboo and carotenoids (Lutein and Zeaxanthin)[10]: a blend of targeted ingredients for a broad, synergistic action on skin wellbeing and hydration.
  • It provides a high content of natural active ingredients.
  • It comes in vegetable capsules that can be opened, making it suitable even for people who have difficulty swallowing.
  • It is packaged in a pharmaceutical-grade dark glass bottle with a reusable safety seal, for optimal storage from the first capsule to the last.
  • It contains no gluten, lactose, colourings, preservatives or synthetic sweeteners, in keeping with Salugea’s philosophy of offering only targeted, 100% natural formulas.

How the synergy of natural ingredients in LuxGea Acido Ialuronico works

The strength of LuxGea Acido Ialuronico lies in its formulation based on 100% natural ingredients. A team of nutrients ready to work together to support hydration, elasticity and skin barrier function.

The skin is, in fact, an organ that is constantly exposed to environmental factors and stress, such as smog, wind and UV rays. That’s why it may need targeted support.

Let’s get to know the key players in the formula.

Dual molecular weight Hyaluronic Acid

LuxGea Acido Ialuronico uses HyaSource® VITA 10K and 100K, which contain hyaluronic acid of different sizes:

  • 10–100 kDa (very low molecular weight)
  • 200–600 kDa (low molecular weight)

Molecular weight indicates the size of the molecule. Using two different fractions is a choice that takes into account how the body absorbs and uses Hyaluronic Acid, promoting its optimal use1.

We can think of Hyaluronic Acid as a magnet, except that instead of attracting metal, it attracts and holds on to water molecules, helping to support skin hydration and elasticity.

In a placebo-controlled study, oral supplementation with Hyaluronic acid for 12 weeks showed an improvement in hydration, elasticity and the appearance of wrinkles in men and women aged between 35 and 64[11].

But its action doesn’t stop there.

Benefits have also been observed on transepidermal water loss (TEWL), which is linked to the skin’s barrier function.

The skin is made up of several layers, and the outermost one, called the skin barrier, helps retain water. When this barrier is less efficient, water evaporates more easily, leaving the skin less hydrated.

The hydrating benefits of Hyaluronic Acid apply to both dry and oily skin[12]. In fact, even oily skin can be dehydrated and need hydration to maintain an even, balanced appearance.

Beta-carotene from Blakeslea trispora

Beta-carotene belongs to the carotenoid family, natural pigments responsible for the yellow-orange colours of many fruits and vegetables. It is probably the best known of them all.

You may have heard people say: “Eat more carrots, or melon, in summer!” The reason? It’s precisely their Beta-carotene content, traditionally associated with skin wellbeing[13] when we spend more time in the sun.

In our body, Beta-carotene is converted into retinol, better known as Vitamin A, which is important for its antioxidant action, for skin wellbeing and for its potential positive effect on skin immunity[14].

A curious fact.

A sociological study[15] observed that a diet rich in carotenoids can influence how the appearance of the skin is perceived. Skin with a slightly warmer tone, due precisely to regular carotenoid consumption, was judged more pleasant and attractive by those observing it.

Lutein and Zeaxanthin from Tagetes erecta

Lutein and Zeaxanthin belong to the carotenoid family, just like Beta-carotene. They are natural pigments found in various plants and are best known for their antioxidant activity.

The compounds found in Tagetes are in fact considered potential allies for the skin, as they help support its defences against oxidative stress[16], a condition that can also be triggered by environmental factors such as smog and UV rays.

It has also been suggested[17] that these compounds may have an anti-ageing and anti-wrinkle action, thanks to their influence on certain enzymes that can damage the structure of the skin.

Vitamin C from Rosehip

Vitamin C and skin really do go hand in hand. Do you know why?
Because Vitamin C performs essential functions for skin wellbeing.

Vitamin C, in fact, contributes to Collagen synthesis and protects cells from oxidative stress.

Collagen is the protein that supports the structure of the skin. When its production is properly supported, the skin can more easily maintain its tone and firmness.

But there’s an even more interesting aspect.

In the LuxGea Acido Ialuronico formula, Vitamin C works in synergy with Vitamin E.

Vitamin E acts against free radicals, helping to neutralise their action. In doing so, however, it is altered and loses some of its activity.

And this is where Vitamin C comes in: it contributes to the regeneration of Vitamin E[18], allowing it to keep playing its role in supporting antioxidant defences.

Vitamin E from Sunflower seed

Vitamin E is an antioxidant that normally accumulates in sebum and in the stratum corneum, the outermost layer of the skin, helping to "shield" cell membranes from oxidative damage[19]-[20].

We can think of each cell as a small room, and of the cell membrane as the wall that protects it and decides what can come in and what must stay out.

Free radicals, on the other hand, can be compared to unwanted guests trying to get in by forcing this “door”, damaging the structure of the membrane.

This is where Vitamin E steps in: with its antioxidant action, it neutralises the negative action of free radicals.

Zinc

Zinc is a very important mineral for our body.
We can think of it as the “on switch” for many little machines working inside the body.

These “machines” are called enzymes, and they are like skilled workers carrying out specific tasks. Without Zinc, many of them would not be able to work efficiently.

Zinc contributes:

  • to the maintenance of normal skin
  • to the protection of cells from oxidative stress
  • to the normal function of the immune system

For the skin, this means supporting the maintenance of its balance.

A possible link has also been suggested between Zinc levels and skin conditions such as atopic dermatitis[21].

Manganese

Manganese is one of those active ingredients that work behind the scenes. You don’t always notice them, but the role they play is essential8.

It contributes to the normal formation of connective tissue and takes part in the processes involved in the synthesis of Collagen and glycosaminoglycans8-[22].

Glycosaminoglycans are long molecules found in the skin and connective tissues. We can picture them as a network that helps retain water and support the tissues. Hyaluronic Acid, for example, belongs to this very family.

Manganese is also a cofactor of an enzyme involved in antioxidant defence mechanisms (MnSOD), helping to protect against oxidative stress, a condition linked to ageing[23].

In other words, it is a strategic active ingredient that can support the structure and wellbeing of the skin over time.

Silicon from Bamboo

In the LuxGea Acido Ialuronico formula, Silicon is provided by Bamboo.

Think of bamboo: that tall, slender plant that bends in the wind but doesn’t break. This very characteristic brings to mind a concept that is fundamental for the skin: elasticity.

Silicon plays a role in the processes involved in Collagen synthesis[24] and contributes to maintaining the structure of connective tissues. Put simply, it helps support the “scaffolding” that gives the skin its shape and firmness.

When this structure is well supported, the skin can stay elastic and smooth over time.

As well as acting on the appearance of wrinkles, Silicon can also have a positive effect on the wellbeing of hair and nails, helping to counter brittleness[25].

An active ingredient with a strong personality… just like Bamboo!

We recommend taking LuxGea Acido Ialuronico:

  • Mid-morning, away from meals*  1 capsule
  • Mid-afternoon, away from meals* 1 capsule

The capsules are of vegetable origin and, if necessary, they can be opened to make them easier to take.

* By "away from meals" we mean at least an hour away from the main meals

Length of the course with LuxGea Acido Ialuronico

You will be able to notice the benefits from the very first weeks of taking it.

We recommend carrying on with the supplementation for three months, to consolidate and maintain the results obtained over time.

We recommend taking LuxGea Acido Ialuronico:

  • Mid-morning, away from meals*  1 capsule
  • Mid-afternoon, away from meals* 1 capsule

The capsules are of vegetable origin and, if necessary, they can be opened to make them easier to take.

* By "away from meals" we mean at least an hour away from the main meals

Length of the course with LuxGea Acido Ialuronico for

You will be able to notice the benefits from the very first weeks of taking it.

We recommend carrying on with the supplementation for three months, to consolidate and maintain the results obtained over time.

Each time you finish a month, we suggest taking a break of 2/3 days before starting the following month. This short break is not compulsory, but it makes the supplementation even more targeted over time!

The supplementation can be repeated in several cycles during the year.

If you would like to, call us at the end of the course! We are interested in you and we want to know how you got on.  Together with our experts you will work out how to approach the following period so as to maintain the benefits!

Each time you finish a month, we suggest taking a break of 2/3 days before starting the following month. This short break is not compulsory, but it makes the supplementation even more targeted over time!

The supplementation can be repeated in several cycles during the year.

If you would like to, call us at the end of the course! We are interested in you and we want to know how you got on.  Together with our experts you will work out how to approach the following period so as to maintain the benefits!

Rosehip (Rosa canina L.) pseudofruit d.e. std. 70% vitamin C, Hydroxypropyl methylcellulose capsule, Bamboo (Bambusa bambos (L.) Voss) shoots d.e. std. 75% silica, Sodium hyaluronate from biofermentation (10-100 kDa), Sodium hyaluronate from biofermentation (200-600 kDa), Marigold (Tagetes erecta L.) flower d.e. std. 20% lutein - 4% zeaxanthin, Vitamin E d-α-Tocopheryl acetate from Sunflower seed oil (Helianthus annuus L.), Zinc bisglycinate, β-Carotene from biofermentation, Manganese bisglycinate, Anti-caking agent: vegetable magnesium stearate. The dry extracts are carried on maltodextrins, maize starch and gum arabic.

AVERAGE AMOUNTS OF NUTRIENTS AND PLANT EXTRACTS IN A DAILY DOSE (2 Capsules)

Rosehip d.e. std.

460 mg

equivalent to Vitamin C

320 mg

400% NRV

Hyaluronic Acid

120 mg

Bamboo d.e. std.

80 mg

equivalent to Silica

60 mg

Marigold d.e. std.

50 mg

equivalent to Lutein

10 mg

equivalent to Zeaxanthin

2 mg

β-Carotene

2.4 mg

equivalent to Vitamin A

400 RE

50% NRV

Vitamin E

12 mg

100% NRV

Zinc

7.5 mg

75% NRV

Manganese

2 mg

100% NRV

NRV: Nutrient Reference Values - RE = Retinol equivalents

The skin is the largest organ in the human body. It covers us completely and is the first point of contact with the outside environment.

It is not the same everywhere: in some areas, such as the soles of the feet, it is thicker, while in others, such as the eye contour, it is much thinner and more delicate.

The skin is made up of several layers, rather like a multi-layered cake.
The main ones are:

  • Epidermis, the outermost layer
  • Dermis, the middle layer
  • Hypodermis, the deepest layer

Each layer carries out a precise function. The epidermis protects, the dermis supports and contains key structural molecules such as collagen, elastin and hyaluronic acid, while the hypodermis contributes to insulation and protection. 

It is constantly exposed to environmental factors such as smog, wind, temperature swings and UV rays, which can leave it subject to oxidative stress and loss of hydration and which, over time, can encourage the appearance of the signs of ageing, such as loss of elasticity and fine lines.

What is Hyaluronic Acid 

Hyaluronic Acid is a molecule naturally present in the human body. It belongs to the glycosaminoglycan family and is one of the main components of the extracellular matrix, the “network” that supports the cells within tissues.

It is found in particular in the dermis, where it helps to maintain the skin’s hydration, elasticity and firmness. It is also present in other structures of the body, such as joints and connective tissues.

Its best-known feature is the ability to bind and retain water3 in large amounts relative to its own weight. This property helps to keep the skin hydrated and smooth in appearance.

Over time, however, the amount of Hyaluronic Acid naturally present in the skin tends to decrease4. This process is associated with a decrease in skin hydration and firmness, which may also show in the appearance of fine lines and wrinkles, often linked to a progressive dehydration of the skin.

Targeted supplementation with Hyaluronic Acid can help to provide an intake of this ingredient and act on the hydration and elasticity of the skin. 

Good habits for skin wellbeing

Skin wellbeing depends on a combination of factors. To support it over time it is important to follow a healthy lifestyle and a varied and balanced diet able to provide vitamins, minerals, an adequate intake of proteins, essential fatty acids and antioxidants.

Daily hydration, regular exercise and proper rest also contribute to skin balance.

It is also advisable to give up smoking and to avoid other habits that can encourage oxidative stress and have a negative impact on the appearance of the skin.

Scientific studies supporting the chosen ingredients 

Hyaluronic Acid 

  • Hsu TF, Su ZR, Hsieh YH, Wang MF, Oe M, Matsuoka R, Masuda Y. Oral Hyaluronan Relieves Wrinkles and Improves Dry Skin: A 12-Week Double-Blinded, Placebo-Controlled Study. Nutrients. 2021 Jun 28;13(7):2220. doi: 10.3390/nu13072220. PMID: 34203487; PMCID: PMC8308347

In this randomised, double-blind, placebo-controlled clinical study, men and women aged between 35 and 64 took hyaluronic acid for 12 weeks.

The results showed a significant improvement in skin hydration and elasticity compared with the placebo group. A reduction in wrinkle depth and a decrease in transepidermal water loss (TEWL) were also observed, suggesting a positive effect on the maintenance of the skin barrier function.

These data support the scientific interest in the oral intake of hyaluronic acid to support skin hydration and appearance.

  • Gao YR, Wang RP, Zhang L, Fan Y, Luan J, Liu Z, Yuan C. Oral administration of hyaluronic acid to improve skin conditions via a randomized double-blind clinical test. Skin Res Technol. 2023 Nov;29(11):e13531. doi: 10.1111/srt.13531. PMID: 38009035; PMCID: PMC10661223

This randomised, double-blind clinical study was carried out to observe the effects of Hyaluronic Acid supplementation.  

After 2–8 weeks a significant improvement in skin hydration was observed compared with placebo, both in dry skin and in oily skin.

Between the 4th and the 8th week an improvement in skin tone was recorded (+3.5%), while after 12 weeks an increase in epidermal thickness was observed (+2.1%).

The results suggest a positive effect of oral Hyaluronic Acid supplementation on skin hydration, structure and parameters.

Beta-carotene

  • Heinrich, U., Gärtner, C., Wiebusch, M., Eichler, O., Sies, H., Tronnier, H., & Stahl, W. (2003). Supplementation with beta-carotene or a similar amount of mixed carotenoids protects humans from UV-induced erythema.. The Journal of nutrition, 133 1, 98-101 . https://doi.org/10.1093/jn/133.1.98

This 12-week study set out to assess the antioxidant activity of Beta-carotene. 

Thirty-six participants, of different sexes and ages, were divided into three groups: one took beta-carotene (24 mg/day), one a mix of carotenoids (beta-carotene 8 mg + lycopene and lutein 8+8 mg) and one placebo. At the end of the study, increased levels of these compounds were observed in the blood and in the skin of the groups that had taken carotenoids, confirming that absorption had taken place.

An improvement compared with placebo was also observed with regard to UV protection. 

  • Ip FW, Lewis GJ, Lefevre CE. Carotenoid skin colouration enhances face and body attractiveness: A cross-cultural study. Q J Exp Psychol (Hove). 2019 Nov;72(11):2565-2573. doi: 10.1177/1747021819850970. Epub 2019 Jun 6. PMID: 31035862

This sociological study assessed how variations in skin colouring influence the perception of the appearance of the skin. The results showed that a skin colouration associated with a higher carotenoid content, tending more towards a rosy and less pale colour, was perceived as more pleasing and attractive. 

Tagetes erecta

  • Maity, N., Nema, N., Abedy, M., Sarkar, B., & Mukherjee, P. Exploring Tagetes erecta Linn flower for the elastase, hyaluronidase and MMP-1 inhibitory activity.. Journal of ethnopharmacology. 2011; 137 3

In this study the flower extracts of Tagetes erecta were analysed in order to assess their activity towards certain enzymes involved in skin ageing processes. The results showed the ability to inhibit elastase, hyaluronidase and MMP-1, enzymes that take part in the degradation of the skin matrix, that is, of the structure that supports the skin.

  • Burlec, A., Pecio, Ł., Kozachok, S., Mircea, C., Corciovă, A., Vereștiuc, L., Cioancă, O., Oleszek, W., & Hăncianu, M. Phytochemical Profile, Antioxidant Activity, and Cytotoxicity Assessment of Tagetes erecta L. Flowers. Molecules. 2021; 26. https://doi.org/10.3390/molecules26051201

This study analysed the phytochemical profile of Tagetes erecta flowers, identifying more than 50 plant compounds, including polyphenols and flavonoids.

The results suggest that the compounds of Tagetes may contribute to supporting the defences against oxidative stress. 

Vitamin C

  • Duarte TL, Cooke MS, Jones GD. Gene expression profiling reveals new protective roles for vitamin C in human skin cells. Free Radic Biol Med. 2009 Jan 1;46(1):78-87. doi: 10.1016/j.freeradbiomed.2008.09.028. Epub 2008 Oct 9. PMID: 18973801

In this in vitro study the researchers observed dermal fibroblasts, the cells responsible for collagen production and for the structure of the skin.

The cells were exposed to a stable derivative of Vitamin C, called ascorbic acid 2-phosphate (AA2P), in order to assess its effects.

The results showed that Vitamin C can act as a support to Collagen synthesis and can positively influence the activity of fibroblasts.

  • Pasonen-Seppänen S, Suhonen TM, Kirjavainen M, Suihko E, Urtti A, Miettinen M, Hyttinen M, Tammi M, Tammi R. Vitamin C enhances differentiation of a continuous keratinocyte cell line (REK) into epidermis with normal stratum corneum ultrastructure and functional permeability barrier. Histochem Cell Biol. 2001 Oct;116(4):287-97. doi: 10.1007/s004180100312. PMID: 11702187

In this in vitro study the action of Vitamin C on epidermal keratinocytes was observed. An action on transepidermal water loss (TEWL) was recorded, together with an increase in the synthesis of filaggrin, a protein involved in the maintenance of epidermal balance and of the skin barrier function.

Vitamin E

  • Abadie, M., Mahfoudh, M., & Al-Rawi, A. (2025). Systemic Vitamin E in Modern Skin Therapy: A Comprehensive Review. European Journal of Clinical Medicine

This review analyses the role of Vitamin E in the dermatological field, gathering and summarising the available evidence on its use.

Vitamin E is described as an antioxidant of interest for the skin, thanks to its ability to contribute to the protection of cells from oxidative stress.

  • Pincemail J, Meziane S. On the Potential Role of the Antioxidant Couple Vitamin E/Selenium Taken by the Oral Route in Skin and Hair Health. Antioxidants (Basel). 2022 Nov 17;11(11):2270. doi: 10.3390/antiox11112270. PMID: 36421456; PMCID: PMC9686906.

This review analyses the action of Vitamin E in combination with other antioxidants, supporting its relevance for the wellbeing of skin and hair.

Zinc 

  • Gray NA, Dhana A, Stein DJ, Khumalo NP. Zinc and atopic dermatitis: a systematic review and meta-analysis. J Eur Acad Dermatol Venereol. 2019;33(6):1042-1050. doi:10.1111/jdv.15524

This systematic review and meta-analysis analysed the possible correlation between Zinc levels and atopic dermatitis. The results indicate that low serum Zinc levels may be associated with a higher incidence of atopic dermatitis. Further work is needed to confirm the evidence. 

Manganese

  •  G, Shanaida M, Hangan T, Kassym L, Kussainova A, Semenova Y, Gheorghe E, Gontova T, Voloshyn V, Lysiuk R, Voloshyn O, Shanaida V, Peana M. The role of trace elements for the function and health of the skin. J Trace Elem Med Biol. 2025 Jun;89:127674. doi:10.1016/j.jtemb.2025.127674. PMID: 40460725

This review analyses the role of trace elements in skin physiology, highlighting the importance of micronutrients such as Zinc, Copper, Iron, Selenium, Manganese and Silicon.

The authors stress how an adequate balance of trace elements is relevant to supporting the function and the wellbeing of the skin.

  • Haftek M, Abdayem R, Guyonnet-Debersac P. Skin Minerals: Key Roles of Inorganic Elements in Skin Physiological Functions. Int J Mol Sci. 2022 Jun 3;23(11):6267. doi: 10.3390/ijms23116267. PMID: 35682946; PMCID: PMC9181837.

This review highlights how numerous mineral elements play an active role in skin physiology. Mineral ions take part in fundamental processes, such as redox balance and the maintenance of the barrier function of the epidermis.

Silicon

  • Barel A, Calomme M, Timchenko A, De Paepe K, Demeester N, Rogiers V, Clarys P, Vanden Berghe D. Effect of oral intake of choline-stabilized orthosilicic acid on skin, nails and hair in women with photodamaged skin. Arch Dermatol Res. 2005 Oct;297(4):147-53. doi: 10.1007/s00403-005-0584-6. Epub 2005 Oct 26

The placebo-controlled study involved 50 women aged between 40 and 65 with signs of photo-ageing, who were given 10 mg/day of Silicon for 20 weeks.

At the end of the supplementation period a significant improvement in the surface characteristics of the skin was observed. In particular, skin roughness decreased in the group treated with Silicon (-19%). Improvements in the mechanical properties of the skin and a reduction in the brittleness of hair and nails were also recorded.

Our texts are for information purposes only; they are not to be understood as an indication for the diagnosis and treatment of medical conditions and are in no way intended to replace the advice of a doctor.
 

Bibliography

[1] Lee, B. M., Park, S. J., Noh, I., & Kim, C. H. (2021). The effects of the molecular weights of hyaluronic acid on the immune responses. Biomaterials research, 25(1), 27. https://doi.org/10.1186/s40824-021-00228-4

[2] Cyphert, J.M.; Trempus, C.S.; Garantziotis, S. Size Matters: Molecular Weight Specificity of Hyaluronan Effects in Cell Biology. Int. J. Cell Biol. 2015, 2015, 563818

[3] Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: A key molecule in skin aging. Dermatoendocrinol. 2012;4(3):253-258. doi:10.4161/derm.21923.

[4] Longas M.O., Russell C.S., He X.Y. Evidence for structural changes in dermatan sulfate and hyaluronic acid with aging. Carbohydr Res. 1987;159:127–136. doi: 10.1016/S0008-6215(00)90010-7

[5] Muhammad, Parikesit & Novianto, Endi & Setyorini, Mirawati & Legiawati, Lili & Yusharyahya, Shannaz & Menaldi, Sri & Budianti, Windy. (2024). Effectiveness of topical hyaluronic acid of different molecular weights in xerosis cutis treatment in elderly: a double-blind, randomized controlled trial. Archives of Dermatological Research. 316. 329. 10.1007/s00403-024-03003-2.

[6] Duarte TL, Cooke MS, Jones GD. Gene expression profiling reveals new protective roles for vitamin C in human skin cells. Free Radic Biol Med. 2009 Jan 1;46(1):78-87. doi: 10.1016/j.freeradbiomed.2008.09.028. Epub 2008 Oct 9. PMID: 18973801.

[7] Pincemail J, Meziane S. On the Potential Role of the Antioxidant Couple Vitamin E/Selenium Taken by the Oral Route in Skin and Hair Health. Antioxidants (Basel). 2022 Nov 17;11(11):2270. doi: 10.3390/antiox11112270. PMID: 36421456; PMCID: PMC9686906.

[8] Bjørklund G, Shanaida M, Hangan T, Kassym L, Kussainova A, Semenova Y, Gheorghe E, Gontova T, Voloshyn V, Lysiuk R, Voloshyn O, Shanaida V, Peana M. The role of trace elements for the function and health of the skin. J Trace Elem Med Biol. 2025 Jun;89:127674. doi: 10.1016/j.jtemb.2025.127674. Epub 2025 May 24. PMID: 40460725.

[9] Barel A, Calomme M, Timchenko A, De Paepe K, Demeester N, Rogiers V, Clarys P, Vanden Berghe D. Effect of oral intake of choline-stabilized orthosilicic acid on skin, nails and hair in women with photodamaged skin. Arch Dermatol Res. 2005 Oct;297(4):147-53. doi: 10.1007/s00403-005-0584-6. Epub 2005 Oct 26. Erratum in: Arch Dermatol Res. 2006 Apr;297(10):481. Dosage error in article text. Erratum in: Arch Dermatol Res. 2006 Feb;297(8):381. Paepe, K De [corrected to De Paepe, K]. PMID: 16205932.

[10] Maity N, Nema NK, Abedy MK, Sarkar BK, Mukherjee PK. Exploring Tagetes erecta Linn flower for the elastase, hyaluronidase and MMP-1 inhibitory activity. J Ethnopharmacol. 2011 Oct 11;137(3):1300-5. doi: 10.1016/j.jep.2011.07.064. Epub 2011 Aug 5. PMID: 21843618.

[11] Hsu TF, Su ZR, Hsieh YH, Wang MF, Oe M, Matsuoka R, Masuda Y. Oral Hyaluronan Relieves Wrinkles and Improves Dry Skin: A 12-Week Double-Blinded, Placebo-Controlled Study. Nutrients. 2021 Jun 28;13(7):2220. doi: 10.3390/nu13072220. PMID: 34203487; PMCID: PMC8308347

[12] Gao YR, Wang RP, Zhang L, Fan Y, Luan J, Liu Z, Yuan C. Oral administration of hyaluronic acid to improve skin conditions via a randomized double-blind clinical test. Skin Res Technol. 2023 Nov;29(11):e13531. doi: 10.1111/srt.13531. PMID: 38009035; PMCID: PMC10661223

[13] Cho, S., Lee, D., Won, C., Kim, S., Lee, S., Lee, M., & Chung, J. (2010). Differential Effects of

Low-Dose and High-Dose Beta-Carotene Supplementation on the Signs of Photoaging and

Type I Procollagen Gene Expression in Human Skin in vivo. Dermatology, 221, 160 - 171.

https://doi.org/10.1159/000305548.

[14] Roche FC, Harris-Tryon TA. Illuminating the Role of Vitamin A in Skin Innate Immunity and the Skin Microbiome: A Narrative Review. Nutrients. 2021 Jan 21;13(2):302. doi: 10.3390/nu13020302. PMID: 33494277; PMCID: PMC7909803.

[15] Ip FW, Lewis GJ, Lefevre CE. Carotenoid skin colouration enhances face and body attractiveness: A cross-cultural study. Q J Exp Psychol (Hove). 2019 Nov;72(11):2565-2573. doi: 10.1177/1747021819850970. Epub 2019 Jun 6. PMID: 31035862

[16] Burlec AF, Pecio Ł, Kozachok S, Mircea C, Corciovă A, Vereștiuc L, Cioancă O, Oleszek W, Hăncianu M. Phytochemical Profile, Antioxidant Activity, and Cytotoxicity Assessment of Tagetes erecta L. Flowers. Molecules. 2021 Feb 24;26(5):1201. doi: 10.3390/molecules26051201. PMID: 33668106; PMCID: PMC7956293.

[17] Maity, N., Nema, N., Abedy, M., Sarkar, B., & Mukherjee, P. Exploring Tagetes erecta Linn flower for the elastase, hyaluronidase and MMP-1 inhibitory activity.. Journal of ethnopharmacology. 2011; 137 3

[18] Niki E. Interaction of ascorbate and alpha-tocopherol. Ann N Y Acad Sci. 1987;498:186-99. doi: 10.1111/j.1749-6632.1987.tb23761.x. PMID: 3304060.

[19] Wang X, Quinn PJ. Vitamin E and its function in membranes. Prog Lipid Res. 1999 Jul;38(4):309-36. doi: 10.1016/s0163-7827(99)00008-9. PMID: 10793887.

[20] Abadie, M., Mahfoudh, M., & Al-Rawi, A. (2025). Systemic Vitamin E in Modern Skin Therapy: A Comprehensive Review. European Journal of Clinical Medicine

[21] Gray NA, Dhana A, Stein DJ, Khumalo NP. Zinc and atopic dermatitis: a systematic review and meta-analysis. J Eur Acad Dermatol Venereol. 2019;33(6):1042-1050. doi:10.1111/jdv.15524

[22] Haftek M, Abdayem R, Guyonnet-Debersac P. Skin Minerals: Key Roles of Inorganic Elements in Skin Physiological Functions. Int J Mol Sci. 2022 Jun 3;23(11):6267. doi: 10.3390/ijms23116267. PMID: 35682946; PMCID: PMC9181837.

[23] Rinnerthaler M, Bischof J, Streubel MK, Trost A, Richter K. Oxidative stress in aging human skin. Biomolecules. 2015 Apr 21;5(2):545-89. doi: 10.3390/biom5020545. PMID: 25906193; PMCID: PMC4496685.

[24] Reffitt DM, Ogston N, Jugdaohsingh R, Cheung HF, Evans BA, Thompson RP, Powell JJ, Hampson GN. Orthosilicic acid stimulates collagen type 1 synthesis and osteoblastic differentiation in human osteoblast-like cells in vitro. Bone. 2003 Feb;32(2):127-35. doi: 10.1016/s8756-3282(02)00950-x. PMID: 12633784

[25] Barel A, Calomme M, Timchenko A, De Paepe K, Demeester N, Rogiers V, Clarys P, Vanden Berghe D. Effect of oral intake of choline-stabilized orthosilicic acid on skin, nails and hair in women with photodamaged skin. Arch Dermatol Res. 2005 Oct;297(4):147-53. doi: 10.1007/s00403-005-0584-6. Epub 2005 Oct 26

[26] Pasonen-Seppänen S, Suhonen TM, Kirjavainen M, Suihko E, Urtti A, Miettinen M, Hyttinen M, Tammi M, Tammi R. Vitamin C enhances differentiation of a continuous keratinocyte cell line (REK) into epidermis with normal stratum corneum ultrastructure and functional permeability barrier. Histochem Cell Biol. 2001 Oct;116(4):287-97. doi: 10.1007/s004180100312. PMID: 11702187.

[27] Abadie, M., Mahfoudh, M., & Al-Rawi, A. (2025). Systemic Vitamin E in Modern Skin Therapy: A Comprehensive Review. European Journal of Clinical Medicine

[28] N., S., & J., S. Evaluation of Invitro Antioxidant Activity of Flowers of Tagetes erecta.

Phytopathology. 2018; 9. https://doi.org/10.25258/phyto.v9i07.11166

[29] Reffitt DM, Ogston N, Jugdaohsingh R, Cheung HF, Evans BA, Thompson RP, Powell JJ, Hampson GN. Orthosilicic acid stimulates collagen type 1 synthesis and osteoblastic differentiation in human osteoblast-like cells in vitro. Bone. 2003 Feb;32(2):127-35. doi: 10.1016/s8756-3282(02)00950-x. PMID: 12633784.

[30] Haftek M, Abdayem R, Guyonnet-Debersac P. Skin Minerals: Key Roles of Inorganic Elements in Skin Physiological Functions. Int J Mol Sci. 2022 Jun 3;23(11):6267. doi: 10.3390/ijms23116267. PMID: 35682946; PMCID: PMC9181837.

Our texts are for information purposes only; they are not to be understood as an indication for the diagnosis and treatment of medical conditions and are in no way intended to replace the advice of a doctor.

Italian Ministry of Health code:  990387779

Food supplement: read the warnings on the label.
Food supplements should not be used as a substitute for a varied, balanced diet and a healthy lifestyle.

Confronto

Standard Salugea Standard di mercato
Pharmaceutical-grade dark glass bottle ✓ ❌
High content of active ingredients ✓ ❌
Vegetable capsules ✓ ❌
100% natural and pure ✓ ❌
Standardised dry extracts only ✓ ❌

What you won’t find in our formulations

Our idea of 100% natural also includes what we choose not to use.

No GMOs
No Synthetic Additives
No Plastic
No Artificial Sweeteners
No Lactose
No Synthetic Preservatives

Frequently Asked Questions about the Product

Skin hydration is a gradual process in which consistency plays an important role, together with a healthy lifestyle and a balanced diet. The first benefits can be felt after a few weeks of regular intake.

Molecular weight indicates the size of the molecule. LuxGea Acido Ialuronico contains two different fractions (one of very low molecular weight and one of low molecular weight), a formulation choice that takes into account bioavailability and use by the body. This combination allows broader support than formulas that use a single type of Hyaluronic Acid.

Yes. The formula of LuxGea Acido Ialuronico is genderless, so it is suitable for both women and men. Hydration, elasticity and protection from oxidative stress are needs common to both sexes. As time goes by, male skin can also undergo a reduction in Hyaluronic Acid and a loss of tone, because of gradual and continuous exposure to environmental factors. For this reason, targeted supplementation can be a useful support for men too, especially where there is dry skin, signs of ageing or signs of environmental stress. Always combined with a healthy, active lifestyle and a varied and balanced diet.

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