- 1 - Who is it for
- 2 - How to take
- 3 - Ingredients
- 4 - Frequently Asked Questions
Natural Antacid for the stomach
From scientific research comes the Reflugea Range: 100% natural extract food supplements to support the wellbeing of the stomach and oesophagus.
Reflugea Rapido contains ingredients selected for their antacid effect and combined in a 3-in-1 multi-action formulation, designed to provide prompt support on multiple levels of gastric wellbeing.
In particular, the synergy of the ingredients in Reflugea Rapido helps support the control of gastric acidity, soothe the oesophagus and throat mucosa, and aid digestion – even after “heavy” meals.
This is made possible by a blend of plant extracts with a high content of active compounds, combined with carefully measured mineral salts to provide a “barrier” and a buffering effect. In addition, for a complete and targeted action, the formulation is enriched with enzymes selected for their role in the digestive process.
Reflugea Rapido is for an immediate relief – easy to keep in your bag, at the office or by the bedside – with a delicate anise flavour, especially designed to address occasional gastric discomfort quickly and naturally, during the day or at night.
Does stomach acidity keep bothering you?
How can you maintain long-term wellbeing and keep gastric discomfort at bay? Try Reflugea Forte with 100% natural ingredients (Mallow, Prickly Pear, Amla, and Linden), specially designed for a prolonged support of stomach wellbeing.
What does Reflugea Rapido by Salugea contain?
Reflugea Rapido formulation combines 100% natural ingredients with synergistic effects for multi-targeted and fast relief.
Extracts of Amla, Mallow, and Sweet Fennel*have been carefully selected to help control gastric acidity, provide a soothing and emollient action on the digestive tract and the oropharyngeal lining, and support the whole digestive process.
Sodium Alginate* acts as a “barrier” to help protect the oesophageal mucosa from stomach acid reflux, while Potassium bicarbonate, Calcium carbonate, and Magnesium citrate provide a balanced and thorough buffering action against excess acidity.
Papain and Lipase*, naturally derived enzymes, help digest proteins and fats.
Finally, Rice Starch* completes the synergy, supporting the role of Amla in controlling acidity, of Mallow for its soothing effect on the mucous membranes, and of Alginate for its protective action.
Reflugea Rapido contains no artificial colourings, preservatives, or sweeteners. Just like all Salugea supplements, it is truly 100% natural.
*Please refer to the Experimental Phytotherapy section where you will find all the reference studies.
Who is Reflugea Rapido natural antacid formula designed for?
Reflugea Rapido formulation has been designed for:
- anyone looking for a natural antacid for the stomach, to be used as needed,
- those who are seeking fast relief from occasional gastric discomfort, for example after a heavy meal,
- anyone who occasionally feels a “burning” sensation rising from the stomach to the chest and throat, especially when lying down,
- Pregnant women[1] (after the third month of pregnancy) experiencing occasional gastric discomfort due to stomach acidity.
What benefits does Reflugea Rapido antacid formula provide?
Thanks to the 100% natural ingredients in Reflugea Rapido,
- you benefit from a completely natural, multi-action antacid formula,
- the ingredients rapidly neutralise excess stomach acid (thanks to potassium bicarbonate, calcium carbonate, and magnesium citrate),
- they help control the production of stomach acid (Amla and Rice Starch),
- they provide relief and protection for the stomach, oesophagus, and throat (Mallow, Sodium Alginate, Rice Starch),
- the formulation supports digestion and stomach emptying (Fennel, Papain, and Lipase),
- you can finally lie down and sleep peacefully.
Why choose Reflugea Rapido antacid formula?
- 100% natural.
- Acts on three fronts: controls acidity, protects the stomach, oesophagus, and throat, and supports digestion.
- The formulation is
- Provides ingredients that help neutralise stomach acids, regulate their production, and create a “barrier effect” between stomach and oesophagus.
- Contains several carefully measured salts for a deep, yet balanced and gentle buffering action.
- Also provides enzymes that help digest proteins and fats, nutrients that are more complex to break down.
- Contains Amla, Mallow, and Fennel as titrated dry extracts, a preparation that ensures a high and consistent content of active compounds.
- Comes in practical, durable brown pharmaceutical-grade glass bottles. Glass is the only material capable of ensuring the product’s quality and safety over time.
- Suitable for vegans and vegetarians.
- Gluten-free.
- Contains no artificial colourings, flavours, preservatives, or sweeteners.
How does the ingredients in Reflugea Rapido work?
The secret of Reflugea Rapido lies in its completely natural formulation, where each ingredient works in synergy to promote the wellbeing of the stomach, oesophagus, and throat, providing fast-acting relief.
Amla: stomach acidity control
Also known as Indian Gooseberry, Amla is one of the most valued plants in Ayurvedic medicine, recognised for many benefits, including a positive effect on the digestive system.
Today, many of its properties are studied and confirmed by the scientific community as well. Amla is one of the ingredients in Reflugea Rapido because its fruit extract helps control the production of stomach acids[2].
Research has also shown that Amla acts as a natural gastroprotective agent, helping prevent the development of lesions in the stomach and its lining[3], and alleviates common discomforts related to excess acidity, such as heartburn and acid reflux2.
Sodium Alginate: the “barrier effect” between the stomach and oesophagus
Sodium Alginate is a naturally derived substance, extracted from brown seaweed. It is known for its ability to form a gel that “floats” on the stomach content and acts as a barrier between the stomach and the oesophagus. In the event of acid reflux, the gel provides a protective shield, protecting the oesophageal lining from the effects of digestive juices[4].
Studies[5]-[6] highlight its ability to relieve gastric discomforts such as heartburn and regurgitation, and to reduce episodes of acid reflux after meals.
Mallow: soothing and emollient effect on the digestive tract and on the oropharyngeal mucosa.
The etymology of the word “Mallow” already gives clues to its properties. It came to us through Latin, which borrowed it from the Ancient Greek maláchē, a term that shares a root with the adjective malakós, meaning “soft”.
Indeed, Mallow has a soothing and gentle action on the walls of the digestive system, including the stomach, oesophagus, throat, and mouth. In short, Mallow works beneficially on all the areas of the body that can be affected by stomach acidity.
This is thanks to its mucilage, which forms a natural protective biofilm on the mucous membranes[7]-[8]-[9].
Sweet Fennel: supports digestive function
Present in the form of essential oil extracted from its seeds, Sweet Fennel is among Reflugea Rapido ingredients because it helps support the natural digestive process and promotes the elimination of intestinal gas[10]. These actions are particularly useful after occasional heavy meals and in case of post-meal bloating.
Fennel also supports gastrointestinal motility[11], helping the stomach and intestines empty.
Papain and Lipase: for the digestion of proteins and fats
Papain, extracted from the papaya fruit, is a proteolytic enzyme. This means it helps break down proteins – such as those found in meat, milk and pulses – into simpler fragments, making them easier to digest and absorb[12], and easing the workload of the stomach.
Lipase, an enzyme obtained through microbial fermentation, helps support the digestion of fats[13], which are known to slow down the digestive process considerably – particularly after rich, heavy meals.
The presence of these enzymes in the Reflugea Rapido formula is far from insignificant, considering that proteins and fats are macronutrients that are often harder to digest and can contribute to excess stomach acidity.
Potassium bicarbonate, calcium carbonate and magnesium citrate: salts with a buffering action
This trio of buffering salts – potassium bicarbonate, calcium carbonate and magnesium citrate – helps maintain gastric pH balance by neutralising excess acidity. Their synergy allows for fast action while preserving the stomach physiological functions.
The choice to combine different salts is deliberate. It helps avoid excessive concentration of any single mineral while ensuring an effective and balanced action, fully respecting the body’s natural functions.
Rice Starch: a soothing and gentle action that helps control stomach acidity
In the Reflugea Rapido formulation, Rice Starch performs several important functions: together with Mallow, it helps protect the mucous membranes of the digestive system with a soothing and emollient action; together with Amla, it contributes to the control of stomach acidity; and finally, together with Sodium Alginate, it provides a protective “barrier” effect, thanks to a slight gelling action that helps retain excess gastric juices[14].
Please refer to the Experimental Phytotherapy section where you will find all the reference studies.
How to take Reflugea Rapido
Promt response
Chew 1 tablet slowly, 2 to 3 times a day, as needed or before bedtime.
Long-lasting protection
If you frequently experience digestive discomfort related to stomach acidity, talk first to your physician! In addition to using Reflugea Rapido as needed, you can combine it with Reflugea Forte – the Salugea supplement containing ingredients such as Mallow, Prickly Pear, Amla and Linden – a formulation specifically designed to support long-term stomach wellbeing.
At the end of the treatment, give us a call! We care about you and want to know how you got on. Together with our experts, you’ll learn how to manage the period that follows to maintain overtime the results you’ve achieved.
WARNINGS
Supplements should not be considered as substitute for a varied and balanced diet and a healthy lifestyle. Keep out of reach of children under the age of three. Do not exceed the recommended dose. The expiry date refers to the product in its intact packaging, stored in a cool, dry place, away from direct light and heat sources.
Ingredients of the supplement with antacid formula Reflugea Rapido
Calcium carbonate; stabiliser: Sorbitol; Potassium bicarbonate; Sodium alginate; Star anise natural flavour; Magnesium citrate; Rice starch (Oryza sativa L.); Mallow (Malva sylvestris L.) leaves dry extract, titr. to 25% polysaccharides; Fennel (Foeniculum vulgare Mill.) fruits dry extract, titr. to 3% essential oil; Amla (Phyllanthus emblica L.) fruits dry extract, titr. to 30% tannins; Papain enzyme from Carica papaya L.; Lipase enzyme from Aspergillus spp.; anti-caking agent: vegetable magnesium stearate; Silica from bamboo shoots; sweetener: Steviol glycosides (Stevia). Extracts are supported on maltodextrins.
Nutritional Values
|
AVERAGE NUTRIENT AND PLANT EXTRACT INTAKE PER DAILY DOSE (3 tablets) |
|
|
Calcium carbonate |
840 mg |
|
Potassium bicarbonate |
630 mg |
|
Sodium alginate |
600 mg |
|
Magnesium citrate |
165 mg |
|
Rice starch |
150 mg |
|
Mallow titr. d.e. |
150 mg |
|
Equivalent to Polysaccharides |
38 mg |
|
Fennel titr. d.e. |
150 mg |
|
Equivalent to essential oil |
4,5 mg |
|
Amla titr. d.e. |
150 mg |
|
Equivalent to Tannins |
45 mg |
|
Papain |
90 mg |
|
Lipase |
75 mg |
SCIENTIFIC INSIGHTS
Stomach acidity: what a nuisance!
My stomach feels like it’s burning.
Food comes back up.
I can taste acid in my throat.
I have a bitter or sour taste in my mouth.
It gets worse when I lie down.
I feel like there’s something stuck in my throat, but it doesn’t go up or down.
I feel a heaviness in my stomach, like a brick.
These are some of the unpleasant sensations you may experience when there is excess gastric acid or when it tends to flow back towards the oesophagus.
But why does this happen?
What can cause excess stomach acid and the backflow of gastric juices?
Some of the triggering factors include:
- large meals or meals high in fat and sugar
- lying down immediately after eating
- excessive consumption of alcohol or fizzy drinks
- eating too quickly and insufficient chewing
Among the most well-known predisposing[15] factors are also:
- Overweight/obesity
- Cigarette smoking
How common is this problem?
Consider that, according to recent data from SIGE[16] (Italian Society of Gastroenterology and Digestive Endoscopy), in Italy almost 1 in 4 people report experiencing symptoms of stomach acidity at least twice a week.
The most common discomforts include:
- Heartburn
- Pain or discomfort behind the breastbone (chest burning)
- Acid regurgitation, i.e., the backflow of acidic or bitter liquid up to the throat or mouth
- Feeling of fullness or bloating after meals, sometimes accompanied by belching
- Dry, irritating cough, especially at night
- Irritated throat, hoarseness, or lowered voice pitch
- Feeling of a lump in the throat, as if a foreign body is stuck.
If you’ve ever experienced one or more of these discomforts, even occasionally, you’ve probably wished for a remedy that could help you quickly.
But what is the right approach?
Act quickly, yes—but on multiple fronts too!
- Control stomach acidity, in addition to neutralising it
- Create a protective barrier between stomach contents and the oesophageal lining
- Soothe the mucous membranes of the stomach, oesophagus and throat
- Support digestion and gastric emptying
With the ingredients in Reflugea Rapido, you can achieve all these benefits quickly and, most importantly, completely naturally. Let’s see what the studies say.
Experimental Phytotheray
Amla
- Al-Rehaily AJ, Al-Howiriny TA, Al-Sohaibani MO, Rafatullah S. Gastroprotective effects of 'Amla' Emblica officinalis on in vivo test models in rats. Phytomedicine. 2002;9(6):515-522. doi:10.1078/09447110260573146
This animal study evaluated the gastroprotective effect of an orally administered Amla extract. The results showed a significant reduction in stomach lesions and acid secretion, suggesting antisecretory, anti-ulcer and protective effects on the gastric mucosa.
- Karkon Varnosfaderani S, Hashem-Dabaghian F, Amin G, et al. Efficacy and safety of Amla (Phyllanthus emblica L.) in non-erosive reflux disease: a double-blind, randomized, placebo-controlled clinical trial. J Integr Med. 2018;16(2):126-131. doi:10.1016/j.joim.2018.02.008
This clinical study, conducted on 68 patients with typical symptoms of gastroesophageal reflux disease (heartburn, regurgitation and epigastric pain), showed that Amla can reduce the frequency and severity of heartburn and regurgitation in cases of non-erosive reflux.
Sodium Alginate
- Chiu CT, Hsu CM, Wang CC, et al. Randomised clinical trial: sodium alginate oral suspension is non-inferior to omeprazole in the treatment of patients with non-erosive gastroesophageal disease. Aliment Pharmacol Ther. 2013;38(9):1054-1064. doi:10.1111/apt.12482
In this randomised, double-blind clinical study, 195 patients with non-erosive reflux disease were treated for 4 weeks with sodium alginate (three times a day) or omeprazole (once a day). The results showed that sodium alginate is as effective as omeprazole in reducing heartburn and regurgitation, with comparable benefits for quality of life indicators and treatment satisfaction
- Vardar R, Keskin M, Valitova E, Bayrakci B, Yildirim E, Bor S. Effect of alginate in patients with GERD hiatal hernia matters. Dis Esophagus. 2017;30(10):1-7. doi:10.1093/dote/dox039
In this clinical study, 50 patients with gastroesophageal reflux – 18 with hiatal hernia and 32 without – were divided into two groups: after a meal known to trigger reflux, one group received sodium alginate and the other water. Patients were monitored for three hours. During the first hour, alginate significantly reduced episodes of acid reflux: in patients with hiatal hernia, episodes decreased from 13.7 to 6.1; in those without hernia, from 5.5 to 3.5.
Mallow
- Mousavi SM, Hashemi SA, Behbudi G, et al. A Review on Health Benefits of Malva sylvestris L. Nutritional Compounds for Metabolites, Antioxidants, and Anti-Inflammatory, Anticancer, and Antimicrobial Applications. Evid Based Complement Alternat Med. 2021;2021:5548404. Published 2021 Aug 14. doi:10.1155/2021/5548404
This review of studies on the benefits of Mallow highlighted its potential for health, thanks to its antioxidant, anti-inflammatory, anti-tumour, wound-healing, hepatoprotective, antinociceptive (i.e., pain-relieving) and antimicrobial activities.
Fennel
- Asano T, Aida S, Suemasu S, Mizushima T. Anethole restores delayed gastric emptying and impaired gastric accommodation in rodents. Biochem Biophys Res Commun. 2016 Mar 25;472(1):125-30. doi: 10.1016/j.bbrc.2016.02.078. Epub 2016 Feb 23. PMID: 26915803.
The study analysed the effect of anethole – the main component of fennel essential oil – in animal models of functional dyspepsia, a common digestive disorder characterised by a feeling of fullness, bloating, and pain in the upper abdomen after meals. The whole fennel essential oil produced a better functional outcome than anethole alone, confirming its ability to promote gastric emptying.
Papain
- Lee SY, Kang JH, Lee DY, et al. Methods for improving meat protein digestibility in older adults. J Anim Sci Technol. 2023;65(1):32-56. doi:10.5187/jast.2023.e6
- Czelej M, Garbacz K, Czernecki T, Rachwał K, Wawrzykowski J, Waśko A. Whey Protein Enzymatic Breakdown: Synthesis, Analysis, and Discovery of New Biologically Active Peptides in Papain-Derived Hydrolysates. Molecules. 2025;30(7):1451. Published 2025 Mar 25. doi:10.3390/molecules30071451
In these two studies, papain, compared with other proteolytic enzymes, showed the greatest effectiveness in breaking down proteins from animal-based foods, improving their digestibility. Specifically, these are proteins from meat and whey (a component found in products such as yoghurt and fresh dairy)
- Domokos-Szabolcsy É, Alshaal T, Elhawat N, et al. Enhanced Oligopeptide and Free Tryptophan Release from Chickpea and Lentil Proteins: A Comparative Study of Enzymatic Modification with Bromelain, Ficin, and Papain. Plants (Basel). 2024;13(21):3100. Published 2024 Nov 3. doi:10.3390/plants13213100
This in vitro study evaluated the effectiveness of three plant-derived proteolytic enzymes – papain, bromelain and ficin – in improving the digestibility and bioavailability of chickpea and lentil proteins. Papain was found to be the most effective enzyme, performing best in making legume proteins more easily digestible and potentially more bioavailable
Lipase
- Levine ME, Koch SY, Koch KL. Lipase Supplementation before a High-Fat Meal Reduces Perceptions of Fullness in Healthy Subjects. Gut Liver. 2015;9(4):464-469. doi:10.5009/gnl14005
In this clinical study, the effectiveness of a capsule containing acid-resistant lipase was tested on 16 healthy volunteers, compared with a placebo, in reducing digestive discomfort after a high-fat meal. Symptoms were monitored for one hour. The results showed that lipase significantly reduced the subjective feeling of gastric fullness compared with the placebo
Rice starch
- Kong F, Oztop MH, Singh RP, McCarthy MJ. Physical changes in white and brown rice during simulated gastric digestion. J Food Sci. 2011 Aug;76(6):E450-7. doi: 10.1111/j.1750-3841.2011.02271.x. PMID: 22417496
This study examined the behaviour of white and brown rice during simulated gastric digestion. The results showed that white rice absorbs gastric fluids more quickly and breaks down more easily than brown rice. These characteristics promote a faster dispersion of solid content in the stomach, which may help support quicker gastric emptying.
DISCLAIMER
Reflugea Rapido is a dietary supplement: please read the warnings on the label.
The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition.
[1] Reflugea Rapido and Reflugea Forte can also be used during pregnancy (after the third month of gestation). As a precaution, make sure to inform your obstetrician, who knows your medical history best.
[2] Al-Rehaily AJ, Al-Howiriny TA, Al-Sohaibani MO, Rafatullah S. Gastroprotective effects of 'Amla' Emblica officinalis on in vivo test models in rats. Phytomedicine. 2002;9(6):515-522. doi:10.1078/09447110260573146
[3] Sairam K, Rao ChV, Babu MD, Kumar KV, Agrawal VK, K Goel RK. Antiulcerogenic effect of methanolic extract of Emblica officinalis: an experimental study. J Ethnopharmacol. 2002;82(1):1-9. doi:10.1016/s0378-8741(02)00041-7
[4] Chiu CT, Hsu CM, Wang CC, et al. Randomised clinical trial: sodium alginate oral suspension is non-inferior to omeprazole in the treatment of patients with non-erosive gastroesophageal disease. Aliment Pharmacol Ther. 2013;38(9):1054-1064. doi:10.1111/apt.12482
[5] Vardar R, Keskin M, Valitova E, Bayrakci B, Yildirim E, Bor S. Effect of alginate in patients with GERD hiatal hernia matters. Dis Esophagus. 2017 Oct 1;30(10):1-7. doi: 10.1093/dote/dox039. PMID: 28859383.
[6] Chandrasekhara TS, Patra UC, Agarwal PK, Shimpi L, Bose K, Kulkarni S, Patil DR, Swami OC. Rapid Relief of Gastroesophageal Reflux Disease (GERD) Symptoms With Sodium Alginate Antacid Suspension: An Indian Real-World Evidence Study. Cureus. 2025 Mar 3;17(3):e79991. doi: 10.7759/cureus.79991. PMID: 40182346; PMCID: PMC11965474
[7] Mousavi SM. et al. A Review on Health Benefits of Malva sylvestris L. Nutritional Compounds for Metabolites, Antioxidants, and Anti-Inflammatory, Anticancer, and Antimicrobial Applications. Evid Based Complement Alternat Med. 2021 Aug 14;2021:5548404. doi: 10.1155/2021/5548404. PMID: 34434245; PMCID: PMC8382527.
[8] Hamedi A, Rezaei H, Azarpira N, Jafarpour M, Ahmadi F. Effects of Malva sylvestris and Its Isolated Polysaccharide on Experimental Ulcerative Colitis in Rats. J Evid Based Complementary Altern Med. 2016 Jan;21(1):14-22. doi: 10.1177/2156587215589184. Epub 2015 Jun 4. PMID: 26045553.
[9] Seddighfar M, Mirghazanfari SM, Dadpay M. Analgesic and anti-inflammatory properties of hydroalcoholic extracts of Malva sylvestris, Carum carvi or Medicago sativa, and their combination in a rat model. J Integr Med. 2020 Mar;18(2):181-188. doi: 10.1016/j.joim.2020.02.003. Epub 2020 Feb 7. PMID: 32113847.
[10] Portincasa, P., Bonfrate, L., Scribano, M. L., Kohn, A., Caporaso, N., Festi, D., … & Cuomo, R. (2016). Curcumin and fennel essential oil improve symptoms and quality of life in patients with irritable bowel syndrome.
[11] Badgujar, S. B., Patel, V. V., & Bandivdekar, A. H. (2014). Foeniculum vulgare Mill: A review of its botany, phytochemistry, pharmacology, contemporary application, and toxicology
[12] Lee SY, Kang JH, Lee DY, et al. Methods for improving meat protein digestibility in older adults. J Anim Sci Technol. 2023;65(1):32-56. doi:10.5187/jast.2023.e6
[13] Levine ME, Koch SY, Koch KL. Lipase Supplementation before a High-Fat Meal Reduces Perceptions of Fullness in Healthy Subjects. Gut Liver. 2015;9(4):464-469. doi:10.5009/gnl14005
[14] Kong F, Oztop MH, Singh RP, McCarthy MJ. Physical changes in white and brown rice during simulated gastric digestion. J Food Sci. 2011 Aug;76(6):E450-7. doi: 10.1111/j.1750-3841.2011.02271.x. PMID: 22417496
[15] Cleveland Clinic - Home - Health Library - Diseases & Conditions - Acid Reflux & GERD.
[16] Società Italiana di Gastroenterologia ed Endoscopia Digestiva – Home – Archivio – News – Interviste, Comunicati e Rassegne Stampa – Malattia da reflusso gastroesofageo, le Linee guida suggeriscono la terapia e sfatano i miti sui cibi tabù Aprile 2024
I nostri testi hanno scopo divulgativo, non vanno intesi come indicazione di diagnosi e cura di stati patologici e non vogliono sostituirsi in alcun modo al parere del Medico.
Cod. Min. Sal.: 200913
I nostri testi hanno scopo divulgativo, non vanno intesi come indicazione di diagnosi e cura di stati patologici e non vogliono sostituirsi in alcun modo al parere del Medico.
Reflugea Rapido
Antacid for the stomach
Domande Frequenti sull'integratore
Altre Domande?
Se non hai trovato la risposta alla tua domanda, puoi contattarci: