The acronym GERD stands for Gastroesophageal Reflux Disease.
It is a debilitating disorder of the digestive tract. Unfortunately, it is rather widespread as it affects up to 33% of the population, youth included.
Such disorder is announced by specific symptoms:
- stomach acidity,
- impaired function of the esophageal sphincter cardia (the valve that closes the stomach at the top),
- acid burping,
- chest pain (right behind the sternum),
- globus sensation (the feeling of a lump in the throat),
- cough or throat irritation due to the acids flowing back into the oesphagus (reflux),
- discomfort generally increases when you are seated, lie down or shortly after your meals.
What causes reflux?
In a way, GERD is a consequence of today's lifestyle:
- the hustle and bustle of modern life combined with bad lifestyle and bad eating habits, like an excessive consumption of coffee, sugary fizzy and alcoholic drinks,
- smoking,
- permanent stress and nervous tension all day long, at work and at home,
- underlying medical conditions like hiatal hernia,
- weight gain.
And what are the solutions the market suggests?
Most of the supplements available on the market simply focus on temporarily buffering the stomach acidity.
Yet, such approach provides only a temporary solution. In fact, as soon as the buffering effect of the salts ends, you are back to square one!
A correct phytotherapeutic approach should:
- buffer stomach acids and regulate acid secretion,
- protect the stomach walls by lining them with a protection film,
- promote the regeneration of the gastric mucosa,
- relieve stress and emotional strain.
Considering all these parameters, Salugea has created Reflugea Forte, a mix of natural ingredients that not only provide immediate relief by buffering the stomach acids, but they are also effective on the long term by regulating the stomach acid secretion and regenerating the gastric mucosa.
Besides, also the emotional side of the disorder is taken care of. It is a matter of fact that body, mind and environment are inextricably intertwined.
Experimental Phytotherapy
Mallow
- Mousavi SM et al. A Review on Health Benefits of Malva sylvestris L. Nutritional Compounds for Metabolites, Antioxidants, and Anti-Inflammatory, Anticancer, and Antimicrobial Applications. Evidence Based Complement Alternat Med. 2021 Aug 14; 2021: 5548404. doi: 10.1155 / 2021/5548404. PMID: 34434245; PMCID: PMC8382527.
The review considers various studies on Mallow therapeutical uses and benefits, highlighting its antimicrobial, epithelial barrier protective and antioxidant properties.
- Hamedi A et al. Effects of Malva sylvestris and Its Isolated Polysaccharide on Experimental Ulcerative Colitis in Rats. J Evid Based Complementary Altern Med. 2016 Jan; 21 (1): 14-22. doi: 10.1177 / 2156587215589184. Epub 2015 Jun 4. PMID: 26045553.
Tests on rats revealed that Mallow active components have positive effects on ulcerative colitis. Researchers therefore suggest the use of this plant as an effective remedy for patients suffering from ulcerative colitis and to reduce the adverse effects of their medication.
Mucosave ® FG
- Alecci U, Bonina F, Bonina A, Rizza L, Inferrera S, Mannucci C, Calapai G. Efficacy and Safety of a Natural Remedy for the Treatment of Gastroesophageal Reflux: A Double-Blinded Randomized-Controlled Study. Evidence Based Complement Alternat Med. 2016;2016:2581461. doi: 10.1155 / 2016/2581461. Epub 2016 Oct 12. PMID: 27818697; PMCID: PMC5080480
A double-blind clinical study was carried out for two months on 118 people (male/female) split into two groups. The first group was treated with an anti-acid preparation combined with Mucosave® FG (Verum), the second group was treated with an antacid preparation that did not contain Mucosave® FG (placebo). At the end of the test, subjects treated with Verum (the antacid preparation containing Mucosave® FG) experienced a significant improvement of the GERD related quality of life (-56,5%) and a reduction of GERD symptoms (-59.1%) such as heartburn, acid regurgitation, nausea and cough, compared to the placebo group.
- Galati EM et al. Antiulcer activity of Opuntia ficus indica (L.) Mill. (Cactaceae): ultrastructural study. J Ethnopharmacol. 2001 Jun; 76 (1): 1-9. doi: 10.1016 / s0378-8741 (01) 00196-9. PMID: 11378276.
The electron microscope observation of the gastric mucosa protected by the mucilage of the prickly pear leaf has shown an anti-ulcer effect on animals. Most probably, the anti-ulcer effect on animals is due to the mucilage produced by the prickly pear leaves.
- Al-Quraishy S et al. Olive (Olea europaea) leaf methanolic extract prevents HCl / ethanol-induced gastritis in rats by attenuating inflammation and augmenting antioxidant enzyme activities. Biomed Pharmacother. 2017 Jul; 91: 338-349. doi: 10.1016 / j.biopha.2017.04.069. Epub 2017 May 2. PMID: 28463797.
The results of tests on animals show that olive leaf extracts can prevent HCl / ethanol-induced gastritis by attenuating inflammation and oxidant/antioxidant imbalance. Hence, olive leaf extract polyphenols can be useful as a natural treatment against gastritis.
Mastiha resin
- Dabos KJ et al. [2010]: Is Chios mastic gum effective in the treatment of functional dyspepsia? A prospective randomized double-blind placebo-controlled trial. J of Ethnopharmacology, 127 (2): 205–209.
The clinical study against placebo confirms the positive action of Mastiha Resin on dyspepsia due to gastric hyperacidity. Mastiha Resin active ingredients prove to be effective in reducing general stomach pain and, in case of anxiety, they also decrease the perception of dull ache in the upper abdomen and heartburn. Chios mastic therefore significantly improves symptoms in patients with functional dyspepsia, compared to placebo.
- Dabos KJ, Sfika E, Vlatta LJ, Giannikopoulos G. The effect of mastic gum on Helicobacter pylori: a randomized pilot study. Phytomedicine. 2010 Mar; 17 (3-4): 296-9. doi: 10.1016 / j.phymed.2009.09.010. Epub 2009 Oct 29. PMID: 19879118
The study carried out on patients confirms the positive effects of Mastiha resin on the Helicobacter-pilori-induced infection.
Amla
- Al-Rehaily AJ, Al-Howiriny TA, Al-Sohaibani MO, Rafatullah S. Gastroprotective effects of 'Amla' Emblica officinalis on in vivo test models in rats. Phytomedicine. 2002 Sep; 9 (6): 515-22. doi: 10.1078 / 09447110260573146. PMID: 12403160.
The study reveals that Amla significantly inhibits the development of gastric lesions and regulates excessive gastric acid secretion.
- Karkon Varnosfaderani S. et al. Efficacy and safety of Amla (Phyllanthus emblica L.) in non-erosive reflux disease: a double-blind, randomized, placebo-controlled clinical trial. J Integr Med. 2018 Mar; 16 (2): 126-131. doi: 10.1016 / j.joim.2018.02.008. Epub 2018 Feb 13. PMID: 29526236.
This double-blind clinical study has shown that Amla significantly reduces regurgitation and heartburn frequency as well as regurgitation and heartburn severity, compared with the placebo group.
DISCLAIMER
The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition.
1 Alecci U, Bonina F, Bonina A, Rizza L, Inferrera S, Mannucci C, Calapai G. Efficacy and Safety of a Natural Remedy for the Treatment of Gastroesophageal Reflux: A Double-Blinded Randomized-Controlled Study. Evidence Based Complement Alternat Med. 2016;2016:2581461. doi: 10.1155 / 2016/2581461. Epub 2016 Oct 12. PMID: 27818697; PMCID: PMC5080480
I nostri testi hanno scopo divulgativo, non vanno intesi come indicazione di diagnosi e cura di stati patologici e non vogliono sostituirsi in alcun modo al parere del Medico.