How to take

For maximum benefits, we recommend that you take two capsules of Diuresan Formula Potenziata per day.

• Mid-morning, away from main meals*: 1 capsule of Diuresan Formula Potenziata
• Mid-afternoon, away from main meals*: 1 capsule of Diuresan Formula Potenziata.

*“Away from main meals” means at least one hour before or after your meals.

Please Note. You may also take the capsules with some food - a small fruit, some nuts or seeds, some yoghurt or bread, etc. - if you experience stomach discomfort after taking them on an empty stomach.

Duration of treatment with Diuresan Formula Potenziata draining supplement.

After a short time, you will see the results and feel the benefits. We recommend that you continue the treatment for at least three months to reach the best results and keep them over time. Remember to suspend the treatment for 2 to 3 days every 30 days of intake. The suspension is suggested, not compulsory, as it helps keep the ingredient effectiveness high.

At the end of the three-month treatment with 2 capsules, you can just repeat it (for a stronger action) or switch to 1 capsule a day for a few more months to keep all the beneficial effects (maintenance phase).

During the treatment, or at the end of it, please contact us! We care for you and would be very pleased to know how you got on and how you feel. Our Team of experts - Biologists, Nutritionists, Chemists and Naturopathic Doctors - will be happy to help you take the next steps to maintain over time the results you have achieved.

Please Note. As we are all different (and unique!), the dosage can be set according to your specific needs and requirements. Just give us a call or write to us for any kind of information or advice you may require. Our experts shall remain at your fullest disposal ;)

Taken alone, Diuresan Formula Potenziata is extremely effective and gives you excellent results. Yet, for a stronger action, you may want to combine it with:

• Salugea Biosnel Formula Potenziata with specific active ingredients effective on orange-peel skin,
• Salugea Venasal with ingredients that support venous circulation and act on prominent veins and capillaries,
• Salugea Organic Maqui Juice for maximum antioxidative action,
• Salugea Sanuril Formula Potenziata for the well-being of the whole urinary tract.

WARNING

Supplements cannot be considered as a replacement for a balanced diet and a healthy lifestyle. Keep out of reach of children under the age of three. Do not exceed the recommended daily dosage. The expiry date refers to the product intact, stored in a cool and dry place, away from heat and direct sunlight.

Ingredients

Pilosella (Hieracium pilosella L.) herb d.e. titr. to 1% vitexin, Birch (Betula pubescens Ehrh.) leaf d.e. titr. to 2.5% hyperoside, Hydroxypropylmethylcellulose capsule, Orthosiphon (Orthosiphon stamineus Benth) leaf d.e. titr. to 0.2% sinensetin, Ash (Fraxinus excelsior L.) leaf d.e. titr. to 2% chlorogenic acid, Hibiscus (Hibiscus sabdariffa L.) flower d.e. titr. to 2% anthocyanins, Silica from Bamboo shoots, Anti-caking agent: Vegetable magnesium stearate. The extracts are supported on maltodextrins.

Nutritional Values

Scientific Insights

Water retention is not just the body's tendency to retain excess fluids. More precisely, it can be defined as the tendency of cells to retain fluids, toxins and salts ^[4].

When cells fail to get rid of the waste they produce - i.e. toxins, salts, and uric acids - waste concentration increases.

The stagnation of toxins causes interstitial fluids (fluids surrounding cells) to increase which in turn leads to the onset of water retention or swelling of the connective tissue - which in medical terms is called oedema ^[5].

Unlike cellulite, water retention is not just a women’s issue. Men can suffer from it too. But even if—for once—this condition, which also has aesthetic implications, can affect men, it’s still women who tend to experience it more frequently ^[6].

There are several possible causes behind water retention, such as⁵:

• a sedentary lifestyle or, conversely, standing for too long,
• a diet high in sugar, salt, and alcohol,
• dehydration,
• hormone imbalances or specific phases in a woman's life, such as pregnancy and menopause,
• high blood pressure,
• use of certain medications.

Over the years, herbal medicine has increasingly studied these conditions, and several studies highlight the importance of a natural approach.

In the next section, we will go through some of them to understand how and why plant-based active ingredients can help promote diuresis and support the elimination of excess fluids and toxins.

Experimental Phytotherapy

The formulation of Diuresan Formula Potenziata includes Pilosella, Birch, Orthosiphon, Ash and Hibiscus.

Here follow some in-depth studies carried out on these ingredients.

Pilosella

• Stanojević L, Stanković M, Nikolić V, Nikolić L, Ristić D, Canadanovic-Brunet J, Tumbas V. Antioxidant Activity and Total Phenolic and Flavonoid Contents of Hieracium pilosella L. Extracts. Sensors (Basel). 2009;9(7):5702-14. doi: 10.3390/s90705702. Epub 2009 Jul 16. PMID: 22346723; PMCID: PMC3274148.

In this study, researchers confirm that Pilosella is a powerful antioxidant with a remarkable diuretic effect.

Birch

• Raudonė L, Raudonis R, Janulis V, Viškelis P. Quality evaluation of different preparations of dry extracts of birch (Betula pendula Roth) leaves. Nat Prod Res. 2014;28(19):1645-8. doi: 10.1080/14786419.2014.925893. Epub 2014 Jun 17. PMID: 24934103.

This study investigated the effects of Birch in different types of preparations and proved that it is in the form of dry extracts that Pilosella is the most effective.

Orthosiphon

• Ameer OZ, Salman IM, Asmawi MZ, Ibraheem ZO, Yam MF. Orthosiphon stamineus: traditional uses, phytochemistry, pharmacology, and toxicology. J Med Food. 2012 Aug;15(8):678-90. doi: 10.1089/jmf.2011.1973. Epub 2012 Jun 25. PMID: 22846075.

This analysis provides a comprehensive summary of the current chemical, pharmacological, and toxicological research available on Orthosiphon.

Specifically, researchers have found that this plant possesses diuretic, hypouricemic, nephroprotective, antioxidant, anti-inflammatory, hepatoprotective, gastroprotective, antihypertensive, antihyperlipidemic, and antimicrobial properties.

The authors conclude that Orthosiphon has broad traditional and functional uses in various pathophysiological conditions.

Ash tree

• Younis T, Khan MR, Sajid M, Majid M, Zahra Z, Shah NA. Fraxinus xanthoxyloides leaves reduced the level of inflammatory mediators during in vitro and in vivo studies. BMC Complement Altern Med. 2016 Jul 19;16:230. doi: 10.1186/s12906-016-1189-7. PMID: 27430329; PMCID: PMC4949749.

This study highlights the therapeutic potential of Algerian or Afghan Ash leaves against inflammatory disorders thanks to the presence of a chloroform fraction.

• Casadebaig J, Jacob M, Cassanas G, Gaudy D, Baylac G, Puech A. Physicochemical and pharmacological properties of spray-dried powders from Fraxinus excelsior leaf extracts. J Ethnopharmacol. 1989 Sep;26(2):211-6. doi: 10.1016/0378-8741(89)90069-x. PMID: 2601362.

This study confirms that Ash excelsior leaf extracts are effective against body fluid retention and are supportive of the urinary tract function.

• Younis T, Khan MR, Sajid M, Majid M, Zahra Z, Shah NA. Fraxinus xanthoxyloides leaves reduced the level of inflammatory mediators during in vitro and in vivo studies. BMC Complement Altern Med. 2016 Jul 19;16:230. doi: 10.1186/s12906-016-1189-7. PMID: 27430329; PMCID: PMC4949749.

In this research, another property of Ash tree leaves was investigated and confirmed, which is the activity against inflammatory disorders.

Hibiscus

• Da-Costa-Rocha I, Bonnlaender B, Sievers H, Pischel I, Heinrich M. Hibiscus sabdariffa L. - a phytochemical and pharmacological review. Food Chem. 2014 Dec 15;165:424-43. doi: 10.1016/j.foodchem.2014.05.002. Epub 2014 May 27. PMID: 25038696.

This research is a summary of studies that have documented how Hibiscus, in addition to its draining effect, also exhibits antibacterial, antioxidant, nephroprotective, hepatoprotective, hypolipidemic (cholesterol-lowering), and antihypertensive properties.

• Alarcón-Alonso J, Zamilpa A, Aguilar FA, Herrera-Ruiz M, Tortoriello J, Jimenez-Ferrer E. Pharmacological characterization of the diuretic effect of Hibiscus sabdariffa Linn (Malvaceae) extract. J Ethnopharmacol. 2012 Feb 15;139(3):751-6. doi: 10.1016/j.jep.2011.12.005. Epub 2011 Dec 13. PMID: 22178178.

This study highlighted that a compound, quercetin, found in Hibiscus sabdariffa (also known as karkadè) acts on the vascular endothelium by triggering the release of nitric oxide, which increases the kidney vasodilation and thereby promotes kidney filtration. Therefore, the diuretic effect of Hibiscus sabdariffa may be mediated by nitric oxide release.

^[1] July 1, 2014 EMA/HMPC/680373/2013 Committee on Herbal Medicinal Products (HMPC) Assessment report on Hieracium pilosella L., herba (PDF).

^[2] Nat Prod Res. 2014;28(19):1645-8. doi: 10.1080/14786419.2014.925893. Epub 2014 Jun 17. Quality evaluation of different preparations of dry extracts of birch (Betula pendula Roth) leaves. Raudonė L, Raudonis R, Janulis V, Viškelis P.

^[3] Ameer OZ, Salman IM, Asmawi MZ, Ibraheem ZO, Yam MF. Orthosiphon stamineus: traditional uses, phytochemistry, pharmacology, and toxicology. J Med Food. 2012 Aug;15(8):678-90. doi: 10.1089/jmf.2011.1973. Epub 2012 Jun 25. PMID: 22846075.

^[4] Humanitas San Pio X - Leg water retention, how to counteract it? - Dr. Massimo Callegari - 04/07/2017.

^[5] Humanitas Gavazzeni - Medical encyclopedia: Water retention.

^[6] Humanitas Research hospital - Symptoms: Water retention.

I nostri testi hanno scopo divulgativo, non vanno intesi come indicazione di diagnosi e cura di stati patologici e non vogliono sostituirsi in alcun modo al parere del Medico.

Cod. Min. Sal.: 94435